Protein Alignment HisCl1 and GABRD

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: XP_016856425.1
• Gene: GABRD / 2563
• HGNCID: 4084
• Length: 687
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 128/402 - (31%)
• Similarity: 199/402 - (49%)
• Gaps: 45/402 - (11%)

  Fly    67 YDKNRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQYRILDV 131
            |.:|..|.:.|.|..|...:.|.|:|.|:|.:|.|...:||.|||||.||..  |.:.:...||.
Human   286 YARNFRPGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLSY--NHTNETLGLDS 348

  Fly   132 DWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQIC 196
            .::..:|.||.|..|||...||::::.|..:.|..|..:||..::|..::|.|....||.|.|.|
Human   349 RFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKYPMDEQEC 413

  Fly   197 SMMIESLSHTVEDLVFIWNMTDPLVVNTE-IELPQLDI-SNNYTTDCTIEYSTGNFTCLAIVFNL 259
            .:.:||..::.||:|:.|:.:...:...: ::|.|..| |..:||:.....|.|.|..|::.|:|
Human   414 MLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTTELMNFKSAGQFPRLSLHFHL 478

  Fly   260 RRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVK 324
            ||..|.::..:|:||.|:|.|||:||||...|:||||:||:|::||:.|....::.|||..|.:|
Human   479 RRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLTMTTLMVSARSSLPRASAIK 543

  Fly   325 AIDVWMSSCSVFVFLSLMEFAVVN-------NFMGPVATKAMKGYSD-ENISDLDDLKSA----- 376
            |:||:...|.||||.:|:|:|..:       .....|.....:...| .|...|..|.:|
Human   544 ALDVYFWICYVFVFAALVEYAFAHFNADYRKKQKAKVKVSRPRAEMDVRNAIVLFSLSAAGVTQE 608

  Fly   377 -------------LQHHRESIIEPQYDTFCHGHA---------------TAIYIDKFSRFFFPFS 413
                         |.....|:.....:|...|.|               .|..||.::|..||.:
Human   609 LAISRRQRRVPGNLMGSYRSVGVETGETKKEGAARSGGQGGIRARLRPIDADTIDIYARAVFPAA 673

  Fly   414 FFILNIVYWTTF 425
            |..:|::||..:
Human   674 FAAVNVIYWAAY 685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	66/196 (34%)
		Neur_chan_memb	270..>350	CDD:280999	39/86 (45%)
GABRD	XP_016856425.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810