Protein Alignment HisCl1 and Gabrb1

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_037088.1
• Gene: Gabrb1 / 25450
• RGDID: 2649
• Length: 474
• Species: Rattus norvegicus
• Alignment Length: 491
• Identity: 144/491 - (29%)
• Similarity: 234/491 - (47%)
• Gaps: 101/491 - (20%)

  Fly     8 LVEFRCLIALAIYLHALEQSIQHCHCVHGYRNNTESAELVSHYESSLS-LPDILPIPSKTYDKNR 71
            |:.|..::|:.            | |.|.           |:..|::| :.:.:....|.||...
  Rat    12 LLSFPVMVAMV------------C-CAHS-----------SNEPSNMSYVKETVDRLLKGYDIRL 52

  Fly    72 APKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLR---LPENMSEQYRILDVDW 133
            .|...|.|..|...:.|.|:|.::|.:|.|...::..|||:|.||.   :|.|::...|:.|
  Rat    53 RPDFGGPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVAD--- 114

  Fly   134 LHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQICSM 198
              .:|.||.:|.|.||...|.:::.|..:.|:.|.|:||..::|...:|.|....||.|.|.|::
  Rat   115 --QLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTL 177

  Fly   199 MIESLSHTVEDLVFIWNMTDPLVVN-TEIELPQLDISNNYTTDCTIEYSTGNFTCLAIVFNLRRR 262
            .|||..:|.:|:.|.||..:..|.. .:|||||..|.:.......:|::||.:..|::.|.|:|.
  Rat   178 EIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLKRN 242

  Fly   263 LGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKAID 327
            :||.:..||:||.||.::||:||||..:|..|||.||:|::||:.|.:|..:::||.:.||||||
  Rat   243 IGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAID 307

  Fly   328 VWMSSCSVFVFLSLMEFAVVNN-FMGPVATKAMKGYSDENISDLDDLK--------------SAL 377
            :::..|.|||||:|:|:|.||. |.|....|......|::.::.:.|:              |.|
  Rat   308 IYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLSTL 372

  Fly   378 QHHRES--------IIEPQYDTFCHGHATAIY--------------------------------- 401
            :...|:        :.:|:...:.:..|:..|
  Rat   373 EIRNETSGSEVLTGVSDPKATMYSYDSASIQYRKPLSSREGFGRGLDRHGVPGKGRIRRRASQLK 437

  Fly   402 -----------IDKFSRFFFPFSFFILNIVYWTTFL 426
                       |||:||.|||.:|.:.|:|||..::
  Rat   438 VKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYV 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	65/198 (33%)
		Neur_chan_memb	270..>350	CDD:280999	42/80 (53%)
Gabrb1	NP_037088.1	LIC	9..472	CDD:273305	144/488 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810