Protein Alignment HisCl1 and lgc-58

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_001368738.1
• Gene: lgc-58 / 191637
• WormBaseID: WBGene00001587
• Length: 553
• Species: Caenorhabditis elegans
• Alignment Length: 548
• Identity: 146/548 - (26%)
• Similarity: 234/548 - (42%)
• Gaps: 168/548 - (30%)

  Fly    37 YRNNTESAELVSHYESSLSLP------DILPIPSKTYDKNRAPKL---LGQPTVVYFHVTVLSLD 92
            |||:.:       .|:|.|.|      ::|....:.|| |::|.:   ..:.|||...:.:..:.
 Worm    12 YRNSPK-------VEASRSEPVPIYLDNLLNAGRQVYD-NQSPPVQHDKEEVTVVELAMYIEGMS 68

  Fly    93 SINEESMTYVTDIFLAQSWRDPRLRLPENMSEQYRILDVDWLHSIWRPDCFFKNAKKVTFHEMSI 157
            |...::|.:..|::..|.||||  ||..|.:.:..:.|...||.:|:||.:|.||:...|||::.
 Worm    69 SFRTQTMDFQLDVYFQQFWRDP--RLAHNETRRVLVKDKAVLHKMWKPDVYFANARIAEFHEVTQ 131

  Fly   158 PNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQICSMMIESLSHTVEDLVFIWNMTDPLVV 222
            ||..:|:..|.::||.:::::|:.|.:..|.:|.|:|.|.:.|.|.::|.|.||..|...:|:..
 Worm   132 PNFLVWIQPDGSILYDTRISMVVVCTLNLEKWPLDSQRCHLRILSYAYTTEQLVIKWKEDEPITR 196

  Fly   223 NTEIELPQLDISNNYTTDCTIEYSTGNFTCLAIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWI 287
            |..|.:..:.|.:.|...|...||||.::|:...|.::|.:.:|:..:|:|:.||||:||.|||:
 Worm   197 NPNIAMSDMHIVDLYPGLCDGNYSTGTWSCVTAEFFVKREITHHVMQSYVPTTLIVVISWFSFWL 261

  Fly   288 KPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKAIDVWMSSCSVFVFLSLMEFAVVNNFM- 351
            ..||:||||:|.:|:||||:||...::.:||.|||:|||||||.:|.:|||..::||.:||...
 Worm   262 DVEAVPARVSLAITTLLTLSTQANAARMALPEVSYMKAIDVWMGACMMFVFGVMIEFTIVNYAQR 326

  Fly   352 -----------------------GPVATKAMKG-------------------------------- 361
                                   |....|..:|
 Worm   327 QGRKWHRTDAEIVMASSLESVKSGNAEKKPSRGDLGAHARHLFLRLRTNERQHLVEDPPEQIAMN 391

  Fly   362 --------------YSDE---------------------------NISDL--------------- 370
                          :|||                           |:|::
 Worm   392 DTAYDTVSQAYSNSFSDEEAAPVVQPPQNEDAEAQEEVWAEQKETNLSEVWKESDPAERLAHWNE 456

  Fly   371 --DDLKSALQ-----HHRESIIEPQYDTFCH------------------------------GHAT 398
              :|..|.|.     |.|....|...:..|:                              |...
 Worm   457 KENDASSPLMGNGRAHVRYGAAEKMKNRKCNDSSRKKEKWSSAIKQIQKHKRNGSVFGKIAGRNR 521

  Fly   399 AIYIDKFSRFFFPFSFFILNIVYWTTFL 426
            |..||:.||:.||.:|.|.|:.||..:|
 Worm   522 AKKIDQTSRWIFPLTFIIFNLTYWIYYL 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	62/197 (31%)
		Neur_chan_memb	270..>350	CDD:280999	45/79 (57%)
lgc-58	NP_001368738.1	LIC	30..548	CDD:273305	138/520 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276914at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.020