Protein Alignment HisCl1 and lgc-45

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_001335538.1
• Gene: lgc-45 / 189345
• WormBaseID: WBGene00021146
• Length: 1046
• Species: Caenorhabditis elegans
• Alignment Length: 397
• Identity: 135/397 - (34%)
• Similarity: 218/397 - (54%)
• Gaps: 25/397 - (6%)

  Fly    38 RNNTESAELVSHYESS---LSLPDILPIPSKT-YDKNRAPKLL-GQPTVVYFHVTVLSLDSINEE 97
            ||:||..|::|....|   |....|||:.:|. ||...||.:. |...||.|.:.:.|:.:....
 Worm   654 RNDTEVDEILSRTNGSTKNLGGSFILPVLNKNQYDPFSAPIVFQGSAVVVRFGIYIESMSNFQTS 718

  Fly    98 SMTYVTDIFLAQSWRDPRLRLPENMSEQYRILDVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYL 162
            :|.|..||:|..||||.||..|  ..:...:.:.|.|..|||||.||.|||:..|||::..|..:
 Worm   719 TMDYDMDIYLMMSWRDARLVNP--YDKPILVKEEDILEKIWRPDPFFANAKEAEFHEVTFLNFLM 781

  Fly   163 WLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQICSMMIESLSHTVEDLVFIW--NMTDPLVVNTE 225
            .::.|..:||.:::.:..||.:....||||.|.|.::|:|.::.||.:.|.|  ...|.:..|.:
 Worm   782 RIFPDGLVLYETRVKIKPSCNLILCKYPHDKQTCDLLIKSFAYPVETVRFEWFTRRKDAIDKNPD 846

  Fly   226 IELPQLDISNNYTTDCTIEYSTGNFTCLAIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPE 290
            ::||:|.|....||.|..|..:|.|:||..||.|:|.:|:|:..||||::|.::.||:..|:..|
 Worm   847 VKLPELYIDRYETTTCPNERKSGAFSCLRAVFRLKRDVGFHIAQTYIPTSLALMFSWVGVWLPEE 911

  Fly   291 AIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKAIDVWMSSCSVFVFLSLMEFAVVNNFMGPVA 355
            .:..|:.:.:|.||||:|::..:::.||.|||:||||:|....:.|||.:|::...|..|  ...
 Worm   912 FMEGRIGVAITVLLTLSTESAGAREHLPSVSYLKAIDLWFGFITGFVFFTLLQTLFVIGF--DKR 974

  Fly   356 TKAMKGYSDENISDLDDLKSALQHHRESIIE--PQYDTFCHGHATAIYIDKFSRFFFPFSFFILN 418
            ...:|.::....:|:      .:..||::::  .:|      |.|..|:|.|.|.|:|.||.:..
 Worm   975 ANQLKKWAGRKTADI------TEEIREALLQKATRY------HKTGRYLDNFCRVFYPLSFILFL 1027

  Fly   419 IVYWTTF 425
            ::|:..|
 Worm  1028 LMYYFVF 1034

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	71/197 (36%)
		Neur_chan_memb	270..>350	CDD:280999	31/79 (39%)
lgc-45	NP_001335538.1	Neur_chan_LBD	687..>969	CDD:332142	104/283 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_129194
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.770