Protein Alignment HisCl1 and lgc-40

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_508428.2
• Gene: lgc-40 / 188854
• WormBaseID: WBGene00020767
• Length: 494
• Species: Caenorhabditis elegans
• Alignment Length: 505
• Identity: 127/505 - (25%)
• Similarity: 228/505 - (45%)
• Gaps: 115/505 - (22%)

  Fly    21 LHALEQSIQHCHCVHGYRNNTESAELVSHYESSLSLPDILPIPSKTYDKNRAPKLL--------- 76
            ||.:.:.:....|:   .|..|||:|.           .:|:.....||.:...|.
 Worm     3 LHTMIRFLLSVCCI---VNVFESADLA-----------FIPLTKAFLDKLKNETLYNRFATPTQY 53

  Fly    77 -GQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQYRILDVDWLHSIWRP 140
             |.||.|...:.:..:.|.:.::|.|..|::..:.|.|.  ||..|.|....:.|:.....:|.|
 Worm    54 DGVPTNVTLSMFIEGMSSFSAQTMDYHLDVYFQEEWYDH--RLAHNASAPILVRDLTVFKMMWHP 116

  Fly   141 DCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQICSMMIESLSH 205
            |.:|.||:...|.:::..|..:|:|.:..:.|.:::::|.||.|....||.|:|.|::.|.|.::
 Worm   117 DVYFANARSAAFQDITDDNFLVWVYPNGRVWYDARISIVSSCNMDLWKYPLDSQECALRILSYAY 181

  Fly   206 TVEDLVFIWNMTDPLVV---NTEIELPQLDISNNYTTDCTIEYSTGNFTCLAIVFNLRRRLGYHL 267
            .:..|..:|:..:.:..   |.:|.:|.:.:.:..|..|...|:||.::|:..:|.:.|.:.:|:
 Worm   182 PMTVLRLLWSEKEDVPAIDRNPDITMPDMSLKHIRTGYCNGTYATGEWSCMTAIFYVEREMMHHV 246

  Fly   268 FHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKAIDVWMSS 332
            ..||:|:|||||:||.:||::.::.||||:|.:|:|||::||....:.:||.|||:|||||||.|
 Worm   247 MQTYVPTALIVVISWFNFWLEIDSAPARVSLSITTLLTISTQANAVKLALPEVSYMKAIDVWMGS 311

  Fly   333 CSVFVFLSLMEFAV---------------------------------VNNFMGPVAT----KAMK 360
            |..|||..::||.:                                 :::.:..|||    :.::
 Worm   312 CMAFVFGVMIEFTICHYAKNLEMLRGDGQPSLIVDTALSTLFGAARDIDDLVRKVATLNEEEGVR 376

  Fly   361 GYSDENI---------------SDLDDL-------------------KSALQHHRESIIEPQYDT 391
            |..:::|               :..:|:                   |::|...|:.:...::.|
 Worm   377 GDGEQHIALNMLNPEEPRLRSLNQNNDVTANGTRYFVGAERMKRKRSKASLSRLRQQVASMRHAT 441

  Fly   392 F---------------CHGHATAIYIDKFSRFFFPFSFFILNIVYWTTFL 426
            .               ..|...|..||:..|..||..|.:.|:.||:.:|
 Worm   442 IDVSRRAFNWTRALRNLRGRRVAQRIDERCRIVFPMIFLLFNVAYWSFYL 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	52/207 (25%)
		Neur_chan_memb	270..>350	CDD:280999	42/112 (38%)
lgc-40	NP_508428.2	LIC	9..490	CDD:273305	124/496 (25%)
		Neur_chan_LBD	44..242	CDD:280998	50/199 (25%)
		Neur_chan_memb	249..487	CDD:280999	61/237 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276914at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	6	5.880