Protein Alignment HisCl1 and lgc-50

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_498637.3
• Gene: lgc-50 / 188633
• WormBaseID: WBGene00020605
• Length: 491
• Species: Caenorhabditis elegans
• Alignment Length: 459
• Identity: 112/459 - (24%)
• Similarity: 201/459 - (43%)
• Gaps: 88/459 - (19%)

  Fly    52 SSLSLPDILPIPSKTYDKNRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRL 116
            :|::|..::......||.:..|:..|....:..||..:|  .|:|.:..:..|:..::.|:||||
 Worm    28 NSINLGKLIDTLLTDYDTHLLPEAEGVNVTIELHVQGVS--GISEITGDFSLDVMYSEIWQDPRL 90

  Fly   117 RLPE-NMSEQYRILDVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVL 180
            .... |:......|..|:...||.||....|:|..:.|.....|.::.||.:..:....:|.:..
 Worm    91 SFKHLNVCATNITLKSDFRKKIWTPDTCIINSKSSSIHSSPSENTFVILYENGLVWSNFRLNVKT 155

  Fly   181 SCAMKFESYPHDTQICSMMIESLSHTVEDLVFIWNMTDPLVVNTEIELPQLDISNNYTTDCTIEY 245
            .|::..:.:|.|:..|.:::||.|...:::..:|:.. |:.:..::|||..|:....|....:||
 Worm   156 PCSVNLKMFPFDSLSCEIVLESYSFNTDEVRLMWHDV-PITMMEKVELPDFDLIGWSTDHQRLEY 219

  Fly   246 STGNFTCLAIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQN 310
            ..|.:....:.|...||.|::||.:|.|::|.|:.||:.|:....::.||:||||:|||.|..|.
 Worm   220 PNGIWDRAKVKFTFARRYGFYLFQSYFPTSLTVISSWVGFFFDVRSVSARITLGVSSLLALTFQF 284

  Fly   311 TQSQQSLPPVSYVKAIDVWMSSCSVFVFLSLMEFAVV-----------------NNFMGPV-ATK 357
            ....:.||.|||:|.:||||....:|:|.:|:|.|:|                 .:::..: .|:
 Worm   285 GNVLRHLPRVSYIKCLDVWMIFSVIFIFCTLVELAIVCQLNRWERERQIGSKVLGHWLNQIRKTR 349

  Fly   358 AMKGYSDE------------NISDLDDLKSALQHHRE-------SIIEP---------------- 387
            ..:..:||            .|..|..||:|......       :.|:|
 Worm   350 KKESKADEGGGGGVGGLLRKRIPVLAQLKAAATDSNSGAATAMTTAIQPPNTNLNSITNSDNSKL 414

  Fly   388 --------QYDTFCH------GHA-----------------TAIYIDKFSRFFFPFSFFILNIVY 421
                    :::|:.:      .|.                 |::.:|:.|...||.||.|.|:||
 Worm   415 VANNFTSIEHETYAYEKKRGFSHCFQRFVYAICPPDRDWTITSVQVDRCSMIMFPLSFLIFNVVY 479

  Fly   422 WTTF 425
            |:.:
 Worm   480 WSIY 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	47/195 (24%)
		Neur_chan_memb	270..>350	CDD:280999	34/96 (35%)
lgc-50	NP_498637.3	LIC	34..483	CDD:273305	110/451 (24%)
		Neur_chan_LBD	34..237	CDD:280998	48/205 (23%)
		Neur_chan_memb	245..480	CDD:280999	56/234 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810