Protein Alignment HisCl1 and lgc-32

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_508139.2
• Gene: lgc-32 / 188603
• WormBaseID: WBGene00020569
• Length: 390
• Species: Caenorhabditis elegans
• Alignment Length: 386
• Identity: 70/386 - (18%)
• Similarity: 143/386 - (37%)
• Gaps: 71/386 - (18%)

  Fly    56 LPDILPIPSKTYDKNRAPKLLGQPTVVYFHVTVLSLDSI-----NEESMTYVTDIFLAQSWRDPR 115
            :|.::.....|.|::....|||:.:.....:.:.|...|     |..:....|:.|...||.:..
 Worm    12 IPIVVLCDDCTSDEDVIADLLGRNSHSSGEIVIKSNYKIAKWLYNSVAHELSTEGFFEMSWTNTT 76

  Fly   116 LRLPENMSEQYRILDV-DWLHSIWRPDCFF---------KNAKKVTFHEMSIPNHYLWLYHDKTL 170
            |.. .|::..::.:.: ..||..|.|..:|         :|...:..||..            .:
 Worm    77 LDF-TNLNACHKTVRIKSLLHIFWLPHVYFPFSYNLEESRNLYNIEIHESG------------NI 128

  Fly   171 LYMSKLTLVLSCAMKFESYPHDTQICSMMIESLSHTVEDLVFIWNMTD-----PLVVNTEIELPQ 230
            ....:|...:.|..:.:|:|.....|::.              |..|:     .:|:.....:..
 Worm   129 TLSKRLKQSIPCKEQSDSHPFSNNTCTLS--------------WKYTNLDNYQKIVIEPSNLMDS 179

  Fly   231 LDISNN---YTTDCTIEYSTGNFTCLAIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAI 292
            ::..::   ...|.|.|.|..:...|.  :.:.:...|.|.|.:.|:.|.::..|:|..:.|.||
 Worm   180 VEREHSRQFILKDVTFESSGDDEQRLH--YTITQTPQYLLLHFFFPALLFLIPPWLSLLLGPMAI 242

  Fly   293 PARVTLGVTSLLTLATQNTQSQQSLPPVSYVKAIDVWMSSCSVFVFLSLMEFAVVNNF--MGPVA 355
             .|..:.:|||:.|:....::....|..:.:.||.:|.....::|...::|..::..|  ||...
 Worm   243 -TRCIILMTSLILLSNHYDRNVTVFPIDASLNAISIWQLFTYIYVIGIVIELIIITLFASMGRSK 306

  Fly   356 T------KAMKGYSDENISDLDDLKSALQHHRESIIEPQYDTFCHGHATAIYIDKFSRFFF 410
            |      ::.|...:....:::||:........:.        |  ...|:::|..|..||
 Worm   307 TCCFAKRRSAKYEMEPLYEEMNDLRQRKTRKTRNC--------C--RKAALFVDIASFIFF 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	34/217 (16%)
		Neur_chan_memb	270..>350	CDD:280999	18/79 (23%)
lgc-32	NP_508139.2	LIC	61..>286	CDD:273305	46/254 (18%)
		LGIC_ECD	61..>162	CDD:355788	20/127 (16%)
		Cys-loop	140..154	CDD:349787	3/13 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900