Protein Alignment HisCl1 and acc-3

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_508810.2
• Gene: acc-3 / 186307
• WormBaseID: WBGene00018880
• Length: 517
• Species: Caenorhabditis elegans
• Alignment Length: 491
• Identity: 143/491 - (29%)
• Similarity: 210/491 - (42%)
• Gaps: 122/491 - (24%)

  Fly    51 ESSLS------LPDILPIPSK-------------TYDKNRAPKLLGQ------PT----VVYFHV 86
            |.||.      ||...|.|:.             |.||....|||..      |:    :|:..|
 Worm    30 EQSLEENKFFPLPPTTPFPTNAVAATDEDGEELCTSDKTIIEKLLNNYKSFRTPSESGVIVWIEV 94

  Fly    87 TVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPE------NMSEQYRILDVDWLHSIWRPDCFFK 145
            .|..::|:||.:..:..||::.:.|.|..||...      |:|....|||     .||:|:..|.
 Worm    95 WVQEVNSVNEITSDFDMDIYVTELWMDSALRYEHLNPCKYNLSLNSEILD-----QIWKPNTVFI 154

  Fly   146 NAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQICSMMIESLSHTVEDL 210
            |:|....|:....|.:|.:|.:.|:....::.:...|:|.|.::|.|.|.|.:.:||.|:..:::
 Worm   155 NSKSANIHKSPFKNVFLMIYPNGTVWVNYRVQVKGPCSMDFSAFPMDQQSCHLTLESFSYNNQEV 219

  Fly   211 VFIW-NMTDPL-VVNTEIELPQLDISNNYTTDCTIE-YSTGNFTCLAIVFNLRRRLGYHLFHTYI 272
            ...| |.|.|| ::..||.||.. :.:||:|....| |..|.:..|.:.|...||.|:::|..||
 Worm   220 DMQWMNWTTPLSLLKKEIVLPDF-VMSNYSTSLKHEIYPAGVWNELTMTFVFSRRYGWYIFQAYI 283

  Fly   273 PSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKAIDVWMSSCSVFV 337
            |:.|.:.:|||||.:.|:.||||..|||.|||.|..|.....::||.||||||:||||..|..||
 Worm   284 PTYLTIFISWISFCLGPKMIPARTMLGVNSLLALTFQFGNIMRNLPRVSYVKALDVWMLVCLTFV 348

  Fly   338 FLSLMEFAVVNNFMG---------------PVATKAMKGYSDENISDL----------------- 370
            |.||:|.|::.: ||               ..|||..||..:...|.|
 Worm   349 FCSLLELAIIGS-MGARSENRQAQQQKQQDEEATKHQKGRENSTCSHLMSPSSCPNSPRICRNHI 412

  Fly   371 -DDLKSALQHH-------RESIIEPQYDTFCHG-------------------------------- 395
             :|:..:.:.:       |:.:|.....|..|.
 Worm   413 PNDVPQSFKSYGSTDPRMRKRLIIASSSTISHAPNANRSEKVLLLDGLEETQFSQVETKFSSMAS 477

  Fly   396 -----HATAIYIDKFSRFFFPFSFFILNIVYWTTFL 426
                 |.|...||:.|...||..|.:.||:|||.:|
 Worm   478 IKMKKHWTTEEIDRLSMIMFPGLFTLFNIIYWTYYL 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	61/213 (29%)
		Neur_chan_memb	270..>350	CDD:280999	42/79 (53%)
acc-3	NP_508810.2	Neur_chan_LBD	69..512	CDD:332142	132/449 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810