Protein Alignment HisCl1 and lgc-39

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_504821.3
• Gene: lgc-39 / 184265
• WormBaseID: WBGene00017314
• Length: 563
• Species: Caenorhabditis elegans
• Alignment Length: 499
• Identity: 134/499 - (26%)
• Similarity: 224/499 - (44%)
• Gaps: 97/499 - (19%)

  Fly    17 LAIYLHALEQSIQHC----------------HCVHG----YRNNTESAELVSHYESSLSLPDIL- 60
            |..|.|:.||.::..                :.:|.    :::..::.|| ...||...|..::
 Worm    63 LKYYTHSFEQKVRETVRDEEYMLKNLWYDPEYVIHDLCEPHKSGGQTGEL-KWSESGDRLLKVIG 126

  Fly    61 -PIPSKTYDKNRAP-KLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMS 123
             .:....|:...|| :..|:.|.|:..|.:.|:.|...:||.:..|::||..|.|  .||..|.:
 Worm   127 NGVVEDGYNMFMAPGQSQGKRTDVHVAVYIESMSSFKAQSMDFEVDMYLAMGWFD--RRLAHNCT 189

  Fly   124 EQYRILDVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFES 188
            ....:........||.||.:|.|:|.....|::.||..:.:|.|..:....:|.:.|||.|..:.
 Worm   190 HPILVTSKLIADRIWYPDLYFVNSKYAYLQEVTTPNLMVIVYPDGLIFKTMRLDVTLSCMMDLKL 254

  Fly   189 YPHDTQICSMMIESLSHTVEDLVFIWNMT-------DPLVVNTEIELPQLDISNNYTTDCTIEY- 245
            :|.|.|.|.:.|:|.:: :|.:|   |:|       .|:..|.:|:|..:.|:|.....|...|
 Worm   255 FPLDYQECPLTIQSFAY-IEQIV---NLTWRDDPPNFPIGFNPDIKLNDMQITNKRFVKCAGPYP 315

  Fly   246 ---STGNFTCLAIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLA 307
               ....::|:.....::|.:.:|:..||||:.::|.:||:|||:.|.|.|||::|.:||||||.
 Worm   316 MFRGEAAWSCIQGYIVMKRLVLFHIIQTYIPTGMLVSISWMSFWLDPRASPARISLTITSLLTLT 380

  Fly   308 TQNTQSQQSLPPVSYVKAIDVWMSSCSVFVFLSLMEFAVVNNFMGPVAT---------------- 356
            |.:..::|.||.|||:||:|:|::.....:||.|:|::.|:.:|....|
 Worm   381 TMSNGARQDLPQVSYIKALDIWLTFSQALIFLVLLEYSFVSYYMTKRTTDCSHRNMFYEERVQEC 445

  Fly   357 ----KAMKGYSDENI---------SDLDDLKSALQHH---------RES----IIEP-------Q 388
                ||.|...:.|.         |||:..|.:.|..         .||    .:.|       :
 Worm   446 KREEKARKSIVNNNKPVIANNTEGSDLNRNKKSQQFSLTHGISACLNESSALMSVTPVPSRLFTK 510

  Fly   389 YDT-----FC--HGHATAIYIDKFSRFFFPFSFFILNIVYWTTF 425
            :||     .|  .....|..||::||:.||..|.:..:.||..|
 Worm   511 FDTNKPCARCSEKNERIAFKIDEYSRWLFPTVFSLFCVSYWLYF 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	55/206 (27%)
		Neur_chan_memb	270..>350	CDD:280999	38/79 (48%)
lgc-39	NP_504821.3	LIC	119..554	CDD:273305	123/440 (28%)
		Neur_chan_LBD	132..336	CDD:280998	56/209 (27%)
		Neur_chan_memb	343..551	CDD:280999	63/207 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D614790at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	5	4.880