Protein Alignment HisCl1 and acc-2

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_501567.1
• Gene: acc-2 / 183758
• WormBaseID: WBGene00008280
• Length: 445
• Species: Caenorhabditis elegans
• Alignment Length: 446
• Identity: 128/446 - (28%)
• Similarity: 209/446 - (46%)
• Gaps: 49/446 - (10%)

  Fly    11 FRCLIALAIYLHALEQSIQHCHCVHGYRNNTESAELVS-----HYESSLSLP-------DILP-- 61
            |..|..|.:.:...|  :.:...||       ||||||     |:::: ..|       ||:.
 Worm     3 FTLLSTLPVLIITTE--LDYSELVH-------SAELVSSSSYIHHKTN-KKPDNCTRDTDIIDRL 57

  Fly    62 IPSKTYDKNRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPE------ 120
            :....|:|.|.|:..|...||  .:.:.::.||:|.:..:..||::.::|.||.|....
 Worm    58 LNGTGYNKFRIPQEEGMTVVV--EIWIQAITSIDELTNDFDMDIYITETWLDPALNFQTMTPCKG 120

  Fly   121 NMSEQYRILDVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMK 185
            |:|..:::||     .:|.|:..|.|:|....|.....:.:|.|:.:.|::...::.:...|::.
 Worm   121 NLSLNHQVLD-----RLWTPNSCFINSKVAQIHNSPFRSVFLMLFPNGTVMVNYRVRVKGPCSLD 180

  Fly   186 FESYPHDTQICSMMIESLSHTVEDLVFIWNMTDPLVVN-TEIELPQLDISNNYTTDCTIEYSTGN 249
            ..::|.|.|.||::.||.::..:::...|:..:..|.| ::|.||..|:....|......|..|.
 Worm   181 LSNFPLDLQKCSLIYESFNYNRQEVEMRWSDAEHPVFNLSKIMLPDFDLFEIQTERRQEPYPAGM 245

  Fly   250 FTCLAIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQ 314
            :..|.:.....||..::....|:|:.|.:.:|||||.:...|||||..|||.|||.:........
 Worm   246 WDELHVTIIFERRFIWYFMQAYLPTYLTIFISWISFSLGSRAIPARTMLGVNSLLAIVFSFGNIM 310

  Fly   315 QSLPPVSYVKAIDVWMSSCSVFVFLSLMEFAVVNNFM---GPVATKAMKGYSDENISDLDDLKSA 376
            ::||.|||:|.|||||.....|:|.||:|.|:| .||   ..||.|..:.....||| .::....
 Worm   311 RNLPRVSYIKGIDVWMLVSMTFIFCSLLELAIV-GFMVRDETVAKKKQQKKISGNIS-REESPHG 373

  Fly   377 LQHHRESIIEPQYD------TFCHGHATAIYIDKFSRFFFPFSFFILNIVYWTTFL 426
            :...|..:..|...      :.|....|...||..|...||||||:.||:||..::
 Worm   374 IISERRFMFPPGCSESSKSLSSCTSGWTPERIDSISSVMFPFSFFVFNIIYWFYYI 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	48/201 (24%)
		Neur_chan_memb	270..>350	CDD:280999	37/79 (47%)
acc-2	NP_501567.1	Neur_chan_LBD	51..258	CDD:308532	50/213 (23%)
		Neur_chan_memb	267..>347	CDD:308533	38/80 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810