Protein Alignment HisCl1 and glc-4

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_495489.2
• Gene: glc-4 / 182971
• WormBaseID: WBGene00001594
• Length: 500
• Species: Caenorhabditis elegans
• Alignment Length: 512
• Identity: 133/512 - (25%)
• Similarity: 227/512 - (44%)
• Gaps: 128/512 - (25%)

  Fly    14 LIALAIYLHALEQSIQHC-------HCVH--GYRNNTESAELVSHYESSLSLPDILPIPSKTYDK 69
            |:||.:...|.:...:.|       |..:  .:|......:|:..|:::     :.|.....|:.
 Worm    10 LLALLVSSTAKKSKTKSCKRTAFSRHTTNYQAWREQMTVCDLLQDYDAA-----VRPSGRTPYND 69

  Fly    70 NRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPEN---MSEQYRILDV 131
            .|.      ..:|...:.:.|:.:::|::|.:|......|.|.|.|||..|:   :|..||  :.
 Worm    70 TRG------AVMVTTSLNIRSISAVSEKNMEFVAQFRFRQEWYDDRLRFIEHQGLLSSDYR--NF 126

  Fly   132 DWLH-----SIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPH 191
            :::|     |:|.||.||:|.|...:|.::..|.:|.:..|..|:|..:|||.|:|:|....||.
 Worm   127 EFIHVARDQSLWIPDTFFQNEKNGWYHMLNQENRFLKIRSDGKLIYDRRLTLHLACSMHLSRYPM 191

  Fly   192 DTQICSMMIESLSHTVEDLVFIWNMTDPLVVNTEIE------LPQLDISNNYTTDCTIEYSTGNF 250
            |.|.|.:...|.::|..|:.:||::  |.:   :|.      ||..:|::.....||.:.:||.:
 Worm   192 DHQNCEIAFASYAYTTADIEYIWDV--PAI---QIHEGANGALPNFEIASFKNASCTSKTNTGTY 251

  Fly   251 TCLAIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQ 315
            :||.:...|.|...:.|...||||:::|.::|:|:||..::..|||.|.:.:|||:.|.:.....
 Worm   252 SCLKVEIRLNRVFSFFLLQLYIPSSMLVGVAWVSYWIDWKSTAARVPLAIVTLLTMITTSHAINS 316

  Fly   316 SLPPVSYVKAIDVWMSSCSVFVFLSLMEFAVVNNFMGPVATKAMKGYSDE--------------- 365
            :||||||.|:||:|:.:|.||:|.||:|:||||          ..|..||
 Worm   317 NLPPVSYAKSIDIWVGACVVFIFFSLIEYAVVN----------YVGILDEHRQMKKAACNRSRLS 371

  Fly   366 NISDLDDLKSALQ------HHRESII-----------EPQYD--------------------TFC 393
            |:.:.|:...:||      ..::.:|           |..::                    ||
 Worm   372 NVIENDNFGESLQSLTFSPQEKKRLIRRRPKKNMEMQEGDFEAIEMVDRGPPRSAGLMEEGWTF- 435

  Fly   394 HGHATAIY------------------------IDKFSRFFFPFSFFILNIVYWTTFL 426
            |.....:|                        ||..:|..||.:|.:.|..||:.:|
 Worm   436 HDTTDLVYIGQRKRVELVRWCSVLSSRGRAERIDIIARIIFPLAFILFNFAYWSIYL 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	60/208 (29%)
		Neur_chan_memb	270..>350	CDD:280999	38/79 (48%)
glc-4	NP_495489.2	LIC	26..491	CDD:273305	128/493 (26%)
		Neur_chan_LBD	50..258	CDD:280998	62/225 (28%)
		Neur_chan_memb	271..488	CDD:280999	58/227 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276914at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920