Protein Alignment HisCl1 and lgc-55

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_507870.2
• Gene: lgc-55 / 180312
• WormBaseID: WBGene00013746
• Length: 538
• Species: Caenorhabditis elegans
• Alignment Length: 510
• Identity: 123/510 - (24%)
• Similarity: 205/510 - (40%)
• Gaps: 117/510 - (22%)

  Fly    20 YLHALEQSIQHCHCVHGY-RNNTESAELVSHY---------------------ESSLSLPDILPI 62
            |....|.|.|.|.|..|: |.:..|..:||..                     ::..:...||..
 Worm    30 YCKTWENSTQSCECRDGFARISNGSCAMVSDLARGGLGLSQDSEEDEPFCVLGQAEKAATRILTE 94

  Fly    63 PSKTYDKNRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPE------- 120
            ....||:|..||:.|....|  .:.:..:..|:|...:....|..:|.|.||.|....
 Worm    95 LLSKYDRNLVPKMKGVDVDV--ELLIQRVSEISEIQSSSTMHILFSQIWHDPGLSFEHEEGAHCL 157

  Fly   121 -NMSEQYRILDVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAM 184
             |:|..:|::|     :||.|:....|:|....|:...||.:|.::.:.|:....::.:...|.|
 Worm   158 TNLSLSHRMVD-----NIWLPNVCIVNSKGSAIHKSPTPNIFLAIFPNGTVWMNYRVVVESPCEM 217

  Fly   185 KFESYPHDTQICSMMIESLSHTVEDLVFIW-NMTDPLVVNTEIELPQLDISNNYTTDCTIEYSTG 248
            .|..:|.|..:|:.:.||.:..|..:...| ....|:....:::||...::.......|..|..|
 Worm   218 DFSFFPMDRVMCTTIFESYAFNVGKVRLHWKRQGQPVEFIDDVKLPDFHMTKFVHEKATFIYPAG 282

  Fly   249 NFTCLAIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQS 313
            .:..|.|....||..|:::...|:|:..:|::||||||:...::||||||||:||:.|..|.:..
 Worm   283 VWDQLNIKLLFRRSYGFYILQIYLPTYCMVLISWISFWLDRRSLPARVTLGVSSLMALTLQYSNV 347

  Fly   314 QQSLPPVSYVKAIDVWMSSCSVFVFLSLMEFAVVNNFMGPVATKAMKGYSDENISDLDDLKSAL- 377
            .:|||.|||||.:|::|..|.|::|||::|.|||.:.   ...|..:..:|.:....||:|..:
 Worm   348 SRSLPKVSYVKGLDLFMFGCIVYIFLSIVELAVVGSL---EQRKQQRTNADGDFLSDDDIKKNIF 409

  Fly   378 ---------------QHHR----------------------------------ESIIEPQYDTFC 393
                           :||:                                  ||...|:.:...
 Worm   410 QRTFSTKSFKSGYGARHHQFSECASPEDGGEWPKTRTEWAERTYVECPEPEPPESNRHPEVENDS 474

  Fly   394 HGHA--------------------------TAIYIDKFSRFFFPFSFFILNIVYW 422
            :...                          ||..:|:|.:..||.:|...|::||
 Worm   475 NNKMLVLVRQRRASRKRRKRLMSGKLFQRWTAEDMDRFCQKLFPITFTFCNLIYW 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	48/203 (24%)
		Neur_chan_memb	270..>350	CDD:280999	40/79 (51%)
lgc-55	NP_507870.2	Neur_chan_LBD	88..295	CDD:280998	49/213 (23%)
		LIC	90..532	CDD:273305	112/450 (25%)
		Neur_chan_memb	304..>391	CDD:280999	41/89 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810