Protein Alignment HisCl1 and lgc-49

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_505841.2
• Gene: lgc-49 / 179547
• WormBaseID: WBGene00010741
• Length: 457
• Species: Caenorhabditis elegans
• Alignment Length: 395
• Identity: 116/395 - (29%)
• Similarity: 186/395 - (47%)
• Gaps: 58/395 - (14%)

  Fly    67 YDKNRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRL------PENMSEQ 125
            |:|.|.|...|.|..|.|.|..::  ||||.:..:..||::.:.|.||.|:.      .:|:|..
 Worm    67 YNKFRIPNENGVPVQVEFWVQAIT--SINEITNDFEMDIYINEMWLDPALKFDHLNPCKQNLSVS 129

  Fly   126 YRILDVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYP 190
            :::|:     .:|.|:..|.|:|....|:....|.:|.:|.:.|:....::.:...|.:..|.:|
 Worm   130 HQVLE-----QLWTPNSCFVNSKFAEIHDSPFKNVFLMIYPNGTVWVNYRVNVKGPCDLSLELFP 189

  Fly   191 HDTQICSMMIESLSHTVEDLVFIWN--MTDPLVVNTEIELPQLDISNNYTTDCTIEYSTGNFTCL 253
            .|.|.|.::.||.::..:::...||  ..:|:.|..:|.||..::....:|..:..|..|.:..|
 Worm   190 LDIQECHLIYESFNYNNQEVRMRWNEKSAEPVSVTNKIRLPDFELIKIESTRISAPYPAGMWDEL 254

  Fly   254 AIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLP 318
            .:.....||..::....|:|:.|.:.:|||||.:..:|:|||..|||.:||.:..|.....::||
 Worm   255 HVKLVFERRYIWYFMQAYLPTYLTIFISWISFSLGTKAMPARTMLGVNALLAMIFQFGNIMRNLP 319

  Fly   319 PVSYVKAIDVWMSSCSVFVFLSLMEFAVVNNFMGPVATKAMKGYSDENISD----------LDDL 373
            .|||||||||||.....|:||||:|.|:|             ||..:|...          ||:.
 Worm   320 RVSYVKAIDVWMLVSMTFIFLSLLELAIV-------------GYKTKNEEGSKKKCPHKKLLDNF 371

  Fly   374 KSA------------LQHHRES-----IIEPQ-YDTFCHGHATAIYIDKFSRFFFPFSFFILNIV 420
            :::            |...|.|     ||..| :..|.:.....  ||:.|...||..|.|.|||
 Worm   372 EASPAGLCRYEKRFMLPVERRSARWGGIIRFQVFQDFWNWSPEK--IDRVSAIMFPACFAIFNIV 434

  Fly   421 YWTTF 425
            ||:.:
 Worm   435 YWSYY 439

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	51/202 (25%)
		Neur_chan_memb	270..>350	CDD:280999	39/79 (49%)
lgc-49	NP_505841.2	LIC	53..439	CDD:273305	116/393 (30%)
		Neur_chan_LBD	57..264	CDD:280998	52/203 (26%)
		Neur_chan_memb	272..436	CDD:280999	61/178 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810