Protein Alignment HisCl1 and lgc-46

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_497338.2
• Gene: lgc-46 / 175279
• WormBaseID: WBGene00022106
• Length: 508
• Species: Caenorhabditis elegans
• Alignment Length: 517
• Identity: 137/517 - (26%)
• Similarity: 212/517 - (41%)
• Gaps: 114/517 - (22%)

  Fly     9 VEFRCLIALAIYLHALEQSIQHCHCVHGYRNNTES-AELVSHYESSLS-----LPDILPIPSKTY 67
            ::|..|:.|.:..|| .:|:        ||.|:.| ..|..:|:..:.     .|.|.|...:..
 Worm     4 LQFLSLVVLLLMCHA-RKSV--------YRRNSPSLRRLTRNYDWEVDEHGGLKPIINPAKVERA 59

  Fly    68 DKNRA---------------PKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLR 117
            .||.|               .|:.|....|...|.|..:.:|::.:..:..||::.::|.||.|.
 Worm    60 TKNCANDSFILGTIMSNYNRHKIPGGQVDVEVEVWVQEITTISDITSDFQLDIYIYETWYDPALN 124

  Fly   118 LPENMSEQYRI-LDVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLS 181
            .......:|.: |:...|..:|.|:..|.|:|....|:...||.:|.:|.:.|:....:|.|...
 Worm   125 YAFMNPCKYNLSLNSVLLEKLWTPNSCFINSKTADIHKSPFPNIFLMIYANGTVWTNYRLKLQGP 189

  Fly   182 CAMKFESYPHDTQICSMMIESLSHTVEDLVFIWNMTDPLVVNTEIELPQLDISNNYTTDCTIEYS 246
            |.|....:|.|...||:..||.::..:::...|::.....:..::||...::.:.:....|.||.
 Worm   190 CIMDLTKFPFDNVTCSLTFESFNYNTDEVKMDWSVNGVQKMRDKMELADYELVDIHKIRTTEEYP 254

  Fly   247 TGNFTCLAIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNT 311
            .|.:..|.:.|..:||.|:::...|:|:.|.:.:|||||.:..:|||||..|||.|||.:..|..
 Worm   255 AGYWHELTMSFEFKRRAGWYILQAYLPTYLTICISWISFALGSKAIPARTMLGVNSLLAMTFQFG 319

  Fly   312 QSQQSLPPVSYVKAIDVWMSSCSVFVFLSLMEFAVV----------------------------- 347
            ...::||.|||||||||||.||..|||.||:|.|.|
 Worm   320 NIIRNLPRVSYVKAIDVWMLSCMTFVFCSLLELAWVGYLSREEEPTSAKCLQPSAQVAPKPCHPP 384

  Fly   348 ------NN----------------------------------FMGPVATKAMKGYSDE------N 366
                  ||                                  ..|.|| .|||.:|..      |
 Worm   385 PVQQNANNSSVHRRQKQPKNEEESALLSLRDNDYGYIPPGFGLNGNVA-NAMKSFSSSCSCEPTN 448

  Fly   367 ISD--LDDLKSALQHHRESIIEPQYDTFCHGHATAIYIDKFSRFFFPFSFFILNIVYWTTFL 426
            :.:  ||:.::.......|:...|     .....|..||..|.|.|||.|.:.||.||..:|
 Worm   449 VVNLMLDEAETIPTSTSSSLSRKQ-----RREILAHKIDSVSVFMFPFLFVLFNIAYWQHYL 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	48/210 (23%)
		Neur_chan_memb	270..>350	CDD:280999	45/148 (30%)
lgc-46	NP_497338.2	Neur_chan_LBD	73..504	CDD:332142	118/436 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810