Protein Alignment HisCl1 and lgc-34

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_493752.1
• Gene: lgc-34 / 173443
• WormBaseID: WBGene00020836
• Length: 390
• Species: Caenorhabditis elegans
• Alignment Length: 442
• Identity: 98/442 - (22%)
• Similarity: 169/442 - (38%)
• Gaps: 97/442 - (21%)

  Fly    19 IYLHALEQSIQHC---HCVHGYRNNTES---AELVSHYESSLSLPDILPIPSKTYDKNRAPKLLG 77
            |:|..:..||..|   ...|..|..||.   ..::|.|:|| |.|     |.:.:..|.|
 Worm     4 IFLFLVLLSIGVCSAQKAFHSRRLGTEGQIVGRILSEYDSS-SRP-----PVRDHADNSA----- 57

  Fly    78 QPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQYRILDVDWLHSIWRPDC 142
                 ...:|.:.::.:...:.....|::|.|.|:|.||:...:..|....:.:.....||.||.
 Worm    58 -----ILVITNIFINRLIWHNNYAEVDLYLRQQWQDSRLKYDVDTREGIDEIRLPGNRKIWEPDT 117

  Fly   143 FFKNAKKVTFHEMSI------PNHYLWLYHDKTLL-------YMSKLTLVLSCAMKFESYPHDTQ 194
            :|.:.|:::.:|.:.      |:.|: ...::.||       .|...|......:|..||.:|
 Worm   118 YFTSGKELSRNEKNSKHIVVEPSGYI-RSSERVLLELPYAYGTMFPFTNSRQFTIKLGSYNYD-- 179

  Fly   195 ICSMMIESLSHTVEDLVFIWNMTDPLVVNTEIELPQ------LDISNNYTTDCTIEYSTGNFTCL 253
                        ::|:|::|..:.|||  ..||:.|      |........||...|:.|.::|:
 Worm   180 ------------IDDIVYLWANSPPLV--NPIEVSQDLLKGDLTFEEASAGDCVGNYTVGVYSCI 230

  Fly   254 --AIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPE-AIPARVTLGVTSLLTLATQNTQSQQ 315
              .:.|:.....|  |...::||..:::.||:.|||... ::|..::..|...:..|......:.
 Worm   231 DAHVYFSASTISG--LMSWFLPSLFLLIGSWLHFWIHGSWSVPRTISAAVPFFILAAYYIFMRED 293

  Fly   316 SLPPVSYVKAIDVWMSSCSVFVFLSLMEFAVV----------NNFMGPVATKAMKGYSDENISDL 370
                 ||.:|...|::.|.|..|.|.:|:.:|          ...:||.....| |.:.|.
 Worm   294 -----SYTQAQGAWLAFCLVLTFFSFVEYFLVICCGGRRSIRYKTLGPQEDHPM-GAAKET---- 348

  Fly   371 DDLKSALQHHRESIIEPQYDTFCHGHATAIYIDKFSRFFFPFSFFILNIVYW 422
                          :|..|:..|........||..||..||....:..|:|:
 Worm   349 --------------VEVAYNEGCASFRDNNGIDVISRVAFPIVTIVFLIIYF 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	44/215 (20%)
		Neur_chan_memb	270..>350	CDD:280999	20/90 (22%)
lgc-34	NP_493752.1	LIC	1..388	CDD:273305	98/442 (22%)
		LGIC_ECD_anion	58..237	CDD:349788	41/195 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D614790at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.920