Protein Alignment HisCl1 and Gabrg3

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: XP_017177467.1
• Gene: Gabrg3 / 14407
• MGIID: 95624
• Length: 468
• Species: Mus musculus
• Alignment Length: 480
• Identity: 137/480 - (28%)
• Similarity: 230/480 - (47%)
• Gaps: 75/480 - (15%)

  Fly     6 SKLVEFRCLIALAIYLHALEQSIQHCHCVHGYRNNTES--------AELVSHYESSLSLPDILPI 62
            :||:...||.:   .|||..:.::.       ..|.:|        |......:.:|.|..:|
Mouse     3 AKLLLLLCLFS---GLHARSRRVEE-------DENEDSPSNQKWVLAPKSQDTDVTLILNKLL-- 55

  Fly    63 PSKTYDKNRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQYR 127
              :.|||...|.:..:|||:...:.|.|:..::..:|.|..|||.||:|.|.|||.  |.:.:..
Mouse    56 --REYDKKLRPDIGIKPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLRF--NSTMKIL 116

  Fly   128 ILDVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHD 192
            .|:.:.:..||.||..|:|:|....|.::.||..|.:::|..:||..:||:...|.::..::|.|
Mouse   117 TLNSNMVGLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPMD 181

  Fly   193 TQICSMMIESLSHTVEDLVFIWNMTDPLVVNTEI-ELPQLDISNNYTTDCTIEYSTGNFTCLAIV 256
            ...|.:...|..:..|::::.|........:.:. .|.|.|......|...:..|.|::..:.|.
Mouse   182 AHACPLTFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDFMGLRNTTEIVTTSAGDYVVMTIY 246

  Fly   257 FNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVS 321
            |.|.||:||....||||..|.||:||:|||||.:|.|||.|||:|::||:.|.:|.:::|||.||
Mouse   247 FELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTTLGITTVLTMTTLSTIARKSLPRVS 311

  Fly   322 YVKAIDVWMSSCSVFVFLSLMEFAVVNNF----------------MGPVATK------AMKGYSD 364
            ||.|:|::::.|.:|||.:|||:|.:|.:                :.|.:|:      :::..|:
Mouse   312 YVTAMDLFVTVCFLFVFAALMEYATLNYYSSCRKPTIRKKKTSQLLHPDSTRWIPDRISLQAPSN 376

  Fly   365 ENISDLDDLKSALQHHRESIIEPQYDTFC--------------------------HG--HATAIY 401
            .::.|:......:.....|:...:::..|                          .|  |.....
Mouse   377 YSLLDMRPPPPVMITLNNSMYWQEFEDTCVYECLDGKDCQSFFCCYEECKSGSWRRGRIHIDVSE 441

  Fly   402 IDKFSRFFFPFSFFILNIVYWTTFL 426
            :|.:||.|||.||.:.|:|||..:|
Mouse   442 LDSYSRVFFPTSFLLFNLVYWVGYL 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	55/195 (28%)
		Neur_chan_memb	270..>350	CDD:280999	44/79 (56%)
Gabrg3	XP_017177467.1	LIC	50..465	CDD:273305	125/420 (30%)
		LGIC_ECD_GABAAR_G	71..252	CDD:349801	50/182 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810