Protein Alignment HisCl1 and Gabre

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_059065.2
• Gene: Gabre / 14404
• MGIID: 1330235
• Length: 916
• Species: Mus musculus
• Alignment Length: 423
• Identity: 122/423 - (28%)
• Similarity: 200/423 - (47%)
• Gaps: 72/423 - (17%)

  Fly    67 YDKNRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQYRILDV 131
            ||....|.:..:||||...|.|.||..|:...|.|..||...|:|.|.|||.  |.:.:..||..
Mouse   493 YDHKLRPGIGEKPTVVTVEVIVNSLGPISTPDMEYSIDIIFHQTWYDERLRY--NDTFETLILHG 555

  Fly   132 DWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQIC 196
            :.:..:|.||.||:|:|:...::::|||....::.|..:||..::|:...|::...::|.|:..|
Mouse   556 NVVSQLWIPDTFFRNSKRTQEYDITIPNQMALIHKDGKVLYSVRMTIDARCSLHMLNFPMDSHSC 620

  Fly   197 SMMIESLSHTVEDLVFIW-NMTDPLVVNTEIELPQLDIS--NNYTTDCTIEYSTGNFTCLAIVFN 258
            .:...|.|:...::::.| |....:......:|.:.|.:  ||.|.  .|....|:|..:...||
Mouse   621 PLSFSSFSYDDSEMIYKWENFKLEINAKNTWKLLEFDFTGVNNKTE--IISTPFGDFMVMTFFFN 683

  Fly   259 LRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYV 323
            :.||.|:.:|..|:||::..::||:|||||.||..||.::||:|:||:||..|.|.::.|.|||:
Mouse   684 VSRRFGFIVFQNYVPSSVTTMLSWVSFWIKIEAAAARASVGVSSVLTMATLGTLSCKNFPRVSYL 748

  Fly   324 KAIDVWMSSCSVFVFLSLMEFAVVN--------------------NFMGPVATKA---------- 358
            .|:|.:::.|.|..|.:|:||||:|                    |......|:|
Mouse   749 TALDFYIAICFVLCFCTLLEFAVLNFLTYNNIKRQASLKVYQLPTNSRANARTRARARTRARARA 813

  Fly   359 -----MKGYSDENISDLDDLKSALQHHRESIIEPQ---------YDTF------------CHGHA 397
                 .:.:..|.::..::.:...|....| ..||         |..|            |.|.:
Mouse   814 RARQQQEVFVCEIVTYEENAEEGYQWSPRS-RRPQCPWRRCGRSYVCFRVLRKYFCMAPGCEGGS 877

  Fly   398 -------TAIY-IDKFSRFFFPFSFFILNIVYW 422
                   ..:| :|.:||..||.:||..|::||
Mouse   878 WQRGRICIHVYRLDNYSRVLFPITFFFFNVLYW 910

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	57/197 (29%)
		Neur_chan_memb	270..>350	CDD:280999	38/99 (38%)
Gabre	NP_059065.2	Neur_chan_LBD	482..687	CDD:280998	57/197 (29%)
		LIC	484..912	CDD:273305	122/423 (29%)
		Neur_chan_memb	696..910	CDD:280999	59/214 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900