Protein Alignment HisCl1 and Gabra4

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_001345970.1
• Gene: Gabra4 / 14397
• MGIID: 95616
• Length: 578
• Species: Mus musculus
• Alignment Length: 477
• Identity: 119/477 - (24%)
• Similarity: 193/477 - (40%)
• Gaps: 126/477 - (26%)

  Fly    74 KLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQYRILDVDWLHSIW 138
            ::||..|.|...:.|.|...:::..|.|..|:|..|:|.|.||:. :...|..|:.:: .:..:|
Mouse    92 EILGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKY-DGPIEILRLNNM-MVTKVW 154

  Fly   139 RPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQICSMMIESL 203
            .||.||:|.||...|.|:.||....:..:.|:||..:||:...|.|:...:|.|...|.:...|.
Mouse   155 TPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMDGHACPLKFGSY 219

  Fly   204 SHTVEDLVFIWNMTDPLVVNTEIE---LPQLDISNNYTTDCTIEYSTGNFTCLAIVFNLRRRLGY 265
            ::...::::.|.......|....|   |.|.|:.....:..||:..||.:..:.:.|:|||::||
Mouse   220 AYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSITGEYIVMTVYFHLRRKMGY 284

  Fly   266 HLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVKAIDVWM 330
            .:..||||..:.|::|.:||||..|::|||...|:|::||:.|.:..::.|||.|||..|:|.::
Mouse   285 FMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFI 349

  Fly   331 SSCSVFVFLSLMEFAVVNNFMGPVATKAMKGYS--DENISDLDDLK-----SALQH--------- 379
            :.|..|||.:|:|||.||.|......||.|..|  ...:.....||     ::||:
Mouse   350 AVCFAFVFSALIEFAAVNYFTNIQMQKAKKKISKPPPEVPAAPVLKEKHTETSLQNTHANLNMRK 414

  Fly   380 ------HRESIIEPQYDTFCHGHATAIY------------------------------------- 401
                  |.||.::.:.:...|...|:..
Mouse   415 RTNALVHSESDVKSRTEVGNHSSKTSAVQESSEATPKAHLASSPNPFSRANAAETMSAAARGLSS 479

  Fly   402 --------------------------------------------------------------IDK 404
                                                                          |||
Mouse   480 AASPSPHGTLRPASLGSASTRPAFGSRLGRIKTTVNTTGAAGNVSATPPPPAPPPSGSGTSKIDK 544

  Fly   405 FSRFFFPFSFFILNIVYWTTFL 426
            ::|..||.:|...|:|||..:|
Mouse   545 YARILFPVTFGAFNMVYWVVYL 566

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	53/190 (28%)
		Neur_chan_memb	270..>350	CDD:280999	37/79 (47%)
Gabra4	NP_001345970.1	Neur_chan_LBD	13..565	CDD:332142	118/474 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810