Protein Alignment HisCl1 and Gabra2

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: NP_032092.1
• Gene: Gabra2 / 14395
• MGIID: 95614
• Length: 451
• Species: Mus musculus
• Alignment Length: 400
• Identity: 126/400 - (31%)
• Similarity: 198/400 - (49%)
• Gaps: 51/400 - (12%)

  Fly    67 YDKNRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRL--PENMSEQYRIL 129
            ||....|.|....|.|:.::.|.|...:::..|.|..|:|..|.|:|.||:.  |.|:.....::
Mouse    53 YDNRLRPGLGDSITEVFTNIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLKFKGPMNILRLNNLM 117

  Fly   130 DVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQ 194
                ...||.||.||.|.||...|.|::||..|.:..|.||||..:||:...|.|..|.:|.|..
Mouse   118 ----ASKIWTPDTFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAH 178

  Fly   195 ICSMMIESLSHTVEDLVFIW--NMTDPLVVNTE-IELPQLDISNNYTTDCTIEYSTGNFTCLAIV 256
            .|.:...|.::|..::.:||  |.:|.:.|..: ..|.|.|:........||:.|||.:|.:...
Mouse   179 SCPLKFGSYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKSSTGEYTVMTAH 243

  Fly   257 FNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVS 321
            |:|:|::||.:..||:|..:.|::|.:|||:..|::|||...|||::||:.|.:..::.|||.|:
Mouse   244 FHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVA 308

  Fly   322 YVKAIDVWMSSCSVFVFLSLMEFAVVNNFMGPVATKAMKGYSDENISDLDDLKS-----ALQHHR 381
            |..|:|.:::.|..|||.:|:|||.||.|     ||  :|::.:..|.::|.|.     .:|::.
Mouse   309 YATAMDWFIAVCYAFVFSALIEFATVNYF-----TK--RGWAWDGKSVVNDKKKEKGSVMIQNNA 366

  Fly   382 ESII----------EPQYDTFCHGHAT--------------------AIYIDKFSRFFFPFSFFI 416
            .::.          :|...|......|                    ...||:.||..||..|..
Mouse   367 YAVAVANYAPNLSKDPVLSTISKSATTPEPNKKPENKPAEAKKTFNSVSKIDRMSRIVFPVLFGT 431

  Fly   417 LNIVYWTTFL 426
            .|:|||.|:|
Mouse   432 FNLVYWATYL 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	64/199 (32%)
		Neur_chan_memb	270..>350	CDD:280999	35/79 (44%)
Gabra2	NP_032092.1	LIC	25..440	CDD:273305	124/397 (31%)
		LGIC_ECD_GABAAR_A2	47..249	CDD:349836	64/199 (32%)
		Cys-loop	166..180	CDD:349836	5/13 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	389..408		1/18 (6%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910