Protein Alignment HisCl1 and gabrr3

DIOPT Version :9

• Sequence 1: NP_731632.1
• Gene: HisCl1 / 41426
• FlyBaseID: FBgn0037950
• Length: 426
• Species: Drosophila melanogaster
• Sequence 2: XP_017947352.2
• Gene: gabrr3 / 100487991
• XenbaseID: XB-GENE-6039478
• Length: 481
• Species: Xenopus tropicalis
• Alignment Length: 471
• Identity: 139/471 - (29%)
• Similarity: 219/471 - (46%)
• Gaps: 78/471 - (16%)

  Fly    22 HALEQ---SIQHCHCVH-------------GYRNNTESAELVSHYESS----LSLPDILPIPSKT 66
            |:|.|   |.||.|..|             ..|:|.::|..:...:|:    :....:|.|..
 Frog    23 HSLRQKPYSPQHLHHPHQVVNQEEEHSQPAAMRDNRKNASKMRRIDSTKVRQMKSEQLLRIDD-- 85

  Fly    67 YDKNRAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQYRILDV 131
            :|....|...|....|...|.:.|:|||:|..|.:...::|...|:|.||.. ::.:.:....|.
 Frog    86 HDFAMRPGFGGSAIPVGIDVQIESIDSISEVDMDFTMTLYLRHYWKDERLSF-QSTNNRSMTFDG 149

  Fly   132 DWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFESYPHDTQIC 196
            ..:..||.||.||.::|:...|:.::.|..|.:|.|..:|:..::|:...|.|.|..:|.|||.|
 Frog   150 RLIKKIWVPDVFFVHSKRSFIHDTTMENIMLRVYPDGNVLFSLRITVTAMCFMDFSRFPLDTQNC 214

  Fly   197 SMMIESLSHTVEDLVFIWNM-TDPLVVNTEIELPQLDISNNYTTDCTIEY-STGNFTCLAIVFNL 259
            |:.:||.::..|||:..|.. .:.|..:..|.|.|..|.....::....| |||.:..|.|.|.|
 Frog   215 SLELESYAYNEEDLMLYWKRGNESLKTDEHIALSQFFIEEFSASNGLAFYSSTGWYNRLFINFIL 279

  Fly   260 RRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLLTLATQNTQSQQSLPPVSYVK 324
            ||.:.:.|..:|.|:.|:|::||:||||...|:||||:||:|::||::|..|....|:|.|||:|
 Frog   280 RRHIFFFLLQSYFPAMLMVMLSWVSFWIDRRAVPARVSLGITTVLTMSTIITGVSASMPQVSYIK 344

  Fly   325 AIDVWMSSCSVFVFLSLMEFAVVNNFMGPVATKAMK--GYSDENIS--------------DLD-D 372
            |:||::....:|||||::|:|.||........|.:|  |.|...::              |.| |
 Frog   345 AVDVYLWISFLFVFLSVIEYAAVNYLTTAEERKQLKRRGKSSATLNLEAVQAMAFDGCFHDSDAD 409

  Fly   373 LKSALQHHRESIIEPQYDTFCHGHATAI---------------------------YIDKFSRFFF 410
            |..:: |..||        ...|.|.::                           .||.:||..|
 Frog   410 LNFSM-HSEES--------SSRGRAASVATLDAMRVRRKKSIRGNFGRIILENNHVIDTYSRIIF 465

  Fly   411 PFSFFILNIVYWTTFL 426
            |..:.:.|..||..:|
 Frog   466 PTVYIVFNFFYWGAYL 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HisCl1	NP_731632.1	Neur_chan_LBD	67..262	CDD:280998	60/196 (31%)
		Neur_chan_memb	270..>350	CDD:280999	40/79 (51%)
gabrr3	XP_017947352.2	LIC	77..480	CDD:273305	126/414 (30%)
		LGIC_ECD	98..283	CDD:355788	58/185 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910