DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(3)neo38 and dar1

DIOPT Version :9

Sequence 1:	NP_001262485.1	Gene:	l(3)neo38 / 41423	FlyBaseID:	FBgn0265276	Length:	455	Species:	Drosophila melanogaster
Sequence 2:	NP_001097493.1	Gene:	dar1 / 38436	FlyBaseID:	FBgn0263239	Length:	751	Species:	Drosophila melanogaster

Alignment Length:	436	Identity:	86/436 - (19%)
Similarity:	146/436 - (33%)	Gaps:	101/436 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 GTPPAAAANAAAAAAAAGTDNHVQRYQTNGNHFNQNVPNVSAANNMQYGQNISIPYSQPQGDLNF 94
            |.|||................|:|...::.:......|..::.|...|.|..:.......|. .:
  Fly   362 GLPPAVDVVELQLQQQHQQQQHLQHNNSSSSSPKLATPGDNSGNTSSYQQQYASQLVSGSGG-GY 425

  Fly    95 LN---------------------------AAAAADHKGKIHPKIERDREEVLNQQILQNVNQSWQ 132
            ||                           |||:|.......|..:...::...||..|.:.|...
  Fly   426 LNGSSSNSYGYSWHSSQSFHTKYQIHPPSAAASATASATATPTAQLGAQQQQQQQQQQQLQQLCP 490

  Fly   133 TLA-NTANTVDYSSHLLSATLPISIQHFLKYSETIKKESTGDVLKNGTNLASLALGGVA---LTP 193
            ..| :|.:|  .||.:.|::...:.:|......|......|   ..|:::.:.|....|   .||
  Fly   491 PAAPSTPST--SSSSISSSSASSASRHMFVPPLTPPSSDPG---SPGSSMVAAAAAAAAQRRTTP 550

  Fly   194 SNNGANGGHHNGLVGMDHGGHMTNMTDANGAALTNGASNGVNGNANGTVTNGGAGAVSSSGSVGT 258
            . .....||..||:           .......|..||:.|.|.:...|:|.
  Fly   551 P-PPYQQGHVMGLI-----------NPPPTLQLLGGAATGSNNSCTTTLTT-------------- 589

  Fly   259 TNASGGTGTASGKKTKKKKPPKEKKPRPKPGEI----------RETKALDGSTLYCCPECQMAYP 313
                  ...||..:.::::|.:::.|:.:|...          |.:....|:..:..
  Fly   590 ------LTPASAIQQQQQQPQQQQVPQQQPPPTPRSSGGGRRGRHSHHQPGTAAHIA-------- 640

  Fly   314 DRSLIEQHVISH------AVERRFV--CDI--CNAALKRKDHLTRHKLSHIPDRPHVCN--ICMK 366
              ||:....:.:      .:|:|.:  ||.  |:....:..||..|:..|..::|:.|.  .|..
  Fly   641 --SLMSVRTVRYNRRNNPELEKRRIHHCDFVGCSKVYTKSSHLKAHQRIHTGEKPYTCQWPECEW 703

  Fly   367 SFKRKEQLTLHIVIHSGEKKHVCIECGKGFYRKDHLRKHTRSHIAR 412
            .|.|.::||.|...|:|.|...||.|.:.|.|.|||..|.:.|:.:
  Fly   704 RFARSDELTRHYRKHTGAKPFKCIVCERSFARSDHLALHMKRHLPK 749

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(3)neo38	NP_001262485.1	C2H2 Zn finger	305..325	CDD:275368	2/19 (11%)
		zf-C2H2_8	306..391	CDD:292531	23/96 (24%)
		C2H2 Zn finger	333..353	CDD:275368	6/21 (29%)
		zf-H2C2_2	345..370	CDD:290200	8/26 (31%)
		C2H2 Zn finger	361..381	CDD:275368	7/21 (33%)
		zf-H2C2_2	374..398	CDD:290200	10/23 (43%)
		C2H2 Zn finger	389..409	CDD:275368	9/19 (47%)
dar1	NP_001097493.1	COG5048	641..>724	CDD:227381	22/82 (27%)
		C2H2 Zn finger	671..688	CDD:275368	4/16 (25%)
		zf-H2C2_2	680..707	CDD:290200	8/26 (31%)
		C2H2 Zn finger	696..718	CDD:275368	7/21 (33%)
		zf-H2C2_2	710..735	CDD:290200	10/24 (42%)
		C2H2 Zn finger	726..746	CDD:275368	9/19 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23235
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100