DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment l(3)neo38 and ZBTB12

DIOPT Version :9

Sequence 1:NP_001262485.1 Gene:l(3)neo38 / 41423 FlyBaseID:FBgn0265276 Length:455 Species:Drosophila melanogaster
Sequence 2:NP_862825.1 Gene:ZBTB12 / 221527 HGNCID:19066 Length:459 Species:Homo sapiens


Alignment Length:254 Identity:61/254 - (24%)
Similarity:91/254 - (35%) Gaps:64/254 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly   200 GGHHNGL-VGMDHGGHMTNMTDANGAALTNGASNGV--------------------NGNANGTVT 243
            ||...|| :|...|||:..:..::....|.....||                    .|.|:...|
Human   227 GGLGGGLGIGGSVGGHLGELAQSSVPPSTVAPPQGVVKACYSLSEDAEGEGLLLIPGGRASVGAT 291

  Fly   244 NG----GAGAVSSSGSVGTTNASGGTGTASGKKTKKKKPPKEKKPRPKPGEIRETKALDGSTLYC 304
            :|    .|.|:::.|:.|:..|.|..|                   |.||.......|.......
Human   292 SGLVEAAAVAMAARGAGGSLGAGGSRG-------------------PLPGGFSGGNPLKNIKCTK 337

  Fly   305 CPEC-----QMAYPDRSLIEQHVISHAVERRFVCDICNAALKRKDHLTRHKLSHIPDRPHVCNIC 364
            |||.     ::.:..|:   ||.|       |:|..|........:|.||...|...:.|.|.||
Human   338 CPEVFQGVEKLVFHMRA---QHFI-------FMCPRCGKQFNHSSNLNRHMNVHRGVKSHSCGIC 392

  Fly   365 MKSFKRKEQLTLHIVIHSGEKKHVCIECGKGFYRKDHLRKHTRSHIARRVKSEVSAQNV 423
            .|.|.:|..|..|:.:|||.:.:.|..|...|..|..:|:|.:..     ..:.:|:||
Human   393 GKCFTQKSTLHDHLNLHSGARPYRCSYCDVRFAHKPAIRRHLKEQ-----HGKTTAENV 446

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
l(3)neo38NP_001262485.1 C2H2 Zn finger 305..325 CDD:275368 7/24 (29%)
zf-C2H2_8 306..391 CDD:292531 26/89 (29%)
C2H2 Zn finger 333..353 CDD:275368 5/19 (26%)
zf-H2C2_2 345..370 CDD:290200 10/24 (42%)
C2H2 Zn finger 361..381 CDD:275368 8/19 (42%)
zf-H2C2_2 374..398 CDD:290200 8/23 (35%)
C2H2 Zn finger 389..409 CDD:275368 6/19 (32%)
ZBTB12NP_862825.1 BTB 23..127 CDD:306997
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 153..179
C2H2 Zn finger 335..355 CDD:275368 4/22 (18%)
zf-C2H2 359..381 CDD:306579 6/21 (29%)
COG5048 <361..>448 CDD:227381 27/91 (30%)
C2H2 Zn finger 361..381 CDD:275368 5/19 (26%)
C2H2 Zn finger 389..409 CDD:275368 8/19 (42%)
C2H2 Zn finger 417..435 CDD:275368 6/17 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.