DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6923 and znrf3

DIOPT Version :9

Sequence 1:	NP_001262484.1	Gene:	CG6923 / 41420	FlyBaseID:	FBgn0037944	Length:	1265	Species:	Drosophila melanogaster
Sequence 2:	NP_001295484.1	Gene:	znrf3 / 556813	ZFINID:	ZDB-GENE-070705-263	Length:	866	Species:	Danio rerio

Alignment Length:	162	Identity:	43/162 - (26%)
Similarity:	69/162 - (42%)	Gaps:	27/162 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly  1097 PQQQP----QAQQSPPVMQHMQRQRAIHHHMFHHHYSPL-HLEIGL-----APLSLGSRILI--- 1148
            |.::|    :...:..:|..:.:|:.....:.|....|. :.::|:     ..:||...||:
Zfish   148 PLKRPVVYVKGTDAVKLMNIVNKQKVARARIQHRPPRPTEYFDMGIFLAFFVVVSLVCLILLIKI 212

  Fly  1149 ------APSRPNRGA--TLETIERNTLPHKYRRVRR------PSETDEDAEKCAICLNLFEIENE 1199
                  :.|..||.|  .||.:|......|::..|.      .|.:......|||||..:....|
Zfish   213 KLKQRRSQSSMNRMAIQALEKMETCKFKAKFKGQREASCGASDSVSSSSTSDCAICLEKYIDGEE 277

  Fly  1200 VRRLPCMHLFHTDCVDQWLVTNKHCPICRVDI 1231
            :|.:||.|.||..|||.||:.:..||.||.:|
Zfish   278 LRVIPCAHRFHKKCVDPWLLQHHTCPHCRHNI 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6923	NP_001262484.1	zf-rbx1	<1185..1228	CDD:289448	19/42 (45%)
CG6923	NP_001262484.1	zf-RING_2	1187..1228	CDD:290367	19/40 (48%)
znrf3	NP_001295484.1	zf-RING_2	265..306	CDD:290367	19/40 (48%)
znrf3	NP_001295484.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	790..811
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910