DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6923 and rnf126

DIOPT Version :9

Sequence 1:	NP_001262484.1	Gene:	CG6923 / 41420	FlyBaseID:	FBgn0037944	Length:	1265	Species:	Drosophila melanogaster
Sequence 2:	XP_031753815.1	Gene:	rnf126 / 448402	XenbaseID:	XB-GENE-5960892	Length:	337	Species:	Xenopus tropicalis

Alignment Length:	219	Identity:	51/219 - (23%)
Similarity:	85/219 - (38%)	Gaps:	45/219 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1076 TSG------SGNSSVAAQASMRHLQLQPQQQPQAQQSPPVMQHMQRQRAIHHHMFHHHYSPLHL- 1133
            |||      .|.|....|:..|:...||:.:...:::....:.:.....|...:.:...:|..:
Frog   122 TSGPVEEPRDGESRREHQSRQRYGARQPRARLSTRRAAGRNEGVPTLEGIIQQLVNGIIAPTAMS 186

  Fly  1134 EIGLAPLSLGSRILIAPSRPNR---GAT-LETIERNTLPHKYRRVRRPSETDE------------ 1182
            .:|:.|..      :..|.|..   ||. |:||....|.........|::|::
Frog   187 NLGVGPWG------VLHSNPMDYAWGANGLDTIITQLLNQFENTGPPPADTEKIQALPTIQITEE 245

  Fly  1183 ---DAEKCAICLNLFEIENEVRRLPCMHLFHTDCVDQWLVTNKHCPICRVDIE-----THMP--- 1236
               ...:|.:|...:.:...||:|||.||||.||:..||..:..||:||..:.     |:.|
Frog   246 HVGSGLECPVCKEDYTVGESVRQLPCNHLFHNDCIIPWLEQHDTCPVCRKSLSGQNTATNPPGLT 310

  Fly  1237 -----NDALPPSSSGVPDAANSAA 1255
                 :.:...|||..|...|:||
Frog   311 EMTFSSSSTSSSSSTSPTDENNAA 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6923	NP_001262484.1	zf-rbx1	<1185..1228	CDD:289448	17/42 (40%)
CG6923	NP_001262484.1	zf-RING_2	1187..1228	CDD:290367	17/40 (43%)
rnf126	XP_031753815.1	zinc_ribbon_9	36..66	CDD:405118
rnf126	XP_031753815.1	RING-H2_RNF126	252..295	CDD:319715	18/42 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1249953at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920