DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6923 and zgc:77838

DIOPT Version :9

Sequence 1:	NP_001262484.1	Gene:	CG6923 / 41420	FlyBaseID:	FBgn0037944	Length:	1265	Species:	Drosophila melanogaster
Sequence 2:	XP_005161030.1	Gene:	zgc:77838 / 402980	ZFINID:	ZDB-GENE-040426-1889	Length:	353	Species:	Danio rerio

Alignment Length:	424	Identity:	86/424 - (20%)
Similarity:	126/424 - (29%)	Gaps:	160/424 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   131 EQPSSSTAAIANPPAVHSIP-------------RPKRKKTEPLTME--PESDNDGDAVVASVSGT 180
            |.|.||.:.....|.:.|:|             :|:.....|.:.:  |:.|:|....:.|
Zfish    41 EDPISSQSPDKQAPGLLSMPCLLKELHRDSAPGQPQETAPPPSSTQSGPQEDSDSSVCLRS---- 101

  Fly   181 WPAGAIEEHAMDSTAVVYEVPSSSLQLSNSSFETAPSAVNAYDDVTSSASDTEHGQFAHTRTTNT 245
                                ||||..|.:|             |..|||.:..    |.|:|..
Zfish   102 --------------------PSSSGHLGDS-------------DTLSSAEEVA----APTQTAG- 128

  Fly   246 TTTTSAVQAHKKKASRSNNASNTSSRAVDTDATPSTSAQSRKRQMSQFSYRKSRVLEPENESSDD 310
                       :|:.||::.|:||        |.:.:|:..:.|..|.:.|
Zfish   129 -----------RKSRRSHSESDTS--------TVAMAAKKNRCQEKQVNGR-------------- 160

  Fly   311 GWDLRVHNPVPPIEPTVTIIRGSRGSDEAEIGHTDHNYYNSRCAVAGAPPDSTYIRSASCSTATH 375
               :||..|           |..|.....      ......|.|.|...||  .::.:|.|.:..
Zfish   161 ---VRVRGP-----------RSQRQKQRM------RQLRQKREAAARRKPD--VLQDSSTSDSDI 203

  Fly   376 TTRSVDYGSRIGRRSAATGSPST-SSDQEQE-------QQQRQQQEEIIHEERRHQQSPGQPMHS 432
            |..|            ::.||.| |||.|.|       ...|:..........|.|...|....|
Zfish   204 TAHS------------SSSSPLTASSDNEGETINSHAPAGHRRADTSGASARGRGQLDLGVASGS 256

  Fly   433 MYGVPGES--------RMSWSRAR---------PSDDSVPPRKHARMELPGRSRSKLSSTNFNSF 480
            :.||..|:        |.:..|.|         .|||.:...::..    |||:       .:||
Zfish   257 LGGVLEEALTRFAAMQRQTEERFRVWMDRLTRLHSDDDLSSSENPE----GRSQ-------VSSF 310

  Fly   481 YPGRRGHRTFAEQGNSSGQHHVRFPPSSTPNSNG 514
            .|......|.|....:........||..|...||
Zfish   311 LPSSESQETLAAYQMARLNAMTVPPPPQTAGLNG 344

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6923	NP_001262484.1	zf-rbx1	<1185..1228	CDD:289448
CG6923	NP_001262484.1	zf-RING_2	1187..1228	CDD:290367
zgc:77838	XP_005161030.1	RNF111_N	25..204	CDD:291949	49/259 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574550
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930