DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6923 and Rnf126

DIOPT Version :9

Sequence 1:	NP_001262484.1	Gene:	CG6923 / 41420	FlyBaseID:	FBgn0037944	Length:	1265	Species:	Drosophila melanogaster
Sequence 2:	NP_001028874.1	Gene:	Rnf126 / 314613	RGDID:	1306011	Length:	328	Species:	Rattus norvegicus

Alignment Length:	282	Identity:	58/282 - (20%)
Similarity:	90/282 - (31%)	Gaps:	104/282 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly  1069 PQQQSPATSGSGNSSVAAQASMRHLQLQPQQQPQAQQSPPVMQHMQR------------------ 1115
            |::.....:||..|:  |.........:.:|.|.||..|||:|::.:
  Rat    41 PEETRNTENGSAPST--APTDQNRQPFEVRQGPWAQARPPVLQNVDQHLFTLPQGYSQFAFGIFD 103

  Fly  1116 ---------------------QRAIHHHMFHHHY------------------------------- 1128
                                 .|....|...|.|
  Rat   104 DSFEIPAFPPGAQADDGRDPESRREREHQSRHRYGARQPRARLTARRATGRHEGVPTLEGIIQQL 168

  Fly  1129 -----SPLHL-EIGLAPLSLGSRILIAPSRPNR---GAT-LETI-------ERNTLP-----HKY 1171
                 ||..: .:||.|..      :..|.|..   ||. |:.|       ..||.|     .|.
  Rat   169 VNGIISPAAVPSLGLGPWG------VLHSNPMDYAWGANGLDAIITQLLNQFENTGPPPADKEKI 227

  Fly  1172 RRVRRPSETDE---DAEKCAICLNLFEIENEVRRLPCMHLFHTDCVDQWLVTNKHCPICRVDIET 1233
            :.:.....|:|   ...:|.:|...:.:...||:|||.||||..|:..||..:..||:||..: |
  Rat   228 QALPTVPVTEEHVGSGLECPVCKEDYALGERVRQLPCNHLFHDSCIVPWLEQHDSCPVCRKSL-T 291

  Fly  1234 HMPNDALPPSSSGVPDAANSAA 1255
            .......||..:||..:::|::
  Rat   292 GQNTATNPPGLTGVGFSSSSSS 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6923	NP_001262484.1	zf-rbx1	<1185..1228	CDD:289448	16/42 (38%)
CG6923	NP_001262484.1	zf-RING_2	1187..1228	CDD:290367	16/40 (40%)
Rnf126	NP_001028874.1	zinc_ribbon_9	10..40	CDD:291067
Rnf126	NP_001028874.1	zf-RING_2	245..287	CDD:290367	16/41 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1249953at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010