DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6923 and SPAP32A8.03c

DIOPT Version :9

Sequence 1:	NP_001262484.1	Gene:	CG6923 / 41420	FlyBaseID:	FBgn0037944	Length:	1265	Species:	Drosophila melanogaster
Sequence 2:	NP_594179.1	Gene:	SPAP32A8.03c / 2542072	PomBaseID:	SPAP32A8.03c	Length:	513	Species:	Schizosaccharomyces pombe

Alignment Length:	510	Identity:	106/510 - (20%)
Similarity:	154/510 - (30%)	Gaps:	177/510 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   802 PTVVESDYPPSLQPHPHPHPHFQPSQGGSSRSSLSGALNAAAVAATAAAVQAQTFSDLLSQAHNE 866
            ||.......|:...:|:|:                         ||.|......||  ..|...|
pombe    79 PTDANRTANPNTNSNPNPN-------------------------ATNAQPNPTMFS--TGQFSTE 116

  Fly   867 --------GRAAALEGNRTP---PHTMVHAQ----HQQRQSINPPAPGV----ASNANLAAAVSP 912
                    |.|||..|:.||   |..:..||    .|.....|.|.|..    |.|||...: :|
pombe   117 QGLPNVFFGAAAAQPGSGTPFVMPGIVNAAQIRNFFQNIMGGNAPQPEANSEQARNANTETS-NP 180

  Fly   913 PPPLEMYSGRSTIPHCGSPPFSVRRSEAAYSNRQHYQPQPHQGHQAPQNQMHAHIHPPHRASAIV 977
            |.......|:.   |..|.|........||.|....||..:.....|:.|        ...|.|.
pombe   181 PFASAQTQGQE---HRPSSPNPAEHMTGAYVNTPLNQPPSYAASTQPEFQ--------QTTSPIF 234

  Fly   978 ATSLTPAPPYPVHQNLWYRQQSMQEMHRRHMTPTPIDLSSNAP--------LLTSTLRNGYLHSI 1034
            ::|.||.||.|                 |...||..:..:..|        .:.|...||.||.:
pombe   235 SSSSTPPPPPP-----------------RPSQPTSGESQNTNPRFPFSAQSFVFSVGPNGALHQV 282

  Fly  1035 CSCVHARNGPVSSLDPAYYPPYDAAPAAAAPPPSPQQQSPATSGSGNSSVAAQASMRHLQLQPQQ 1099
                                             :...::|..:.:|...:....|:.........
pombe   283 ---------------------------------NTSTENPQNAQAGAIPITDLGSILERIFGSLN 314

  Fly  1100 QPQAQQSPPVMQHMQRQRAIHHHMFHHHYSPLHLEIGLAPLSLGSRILIAPSRPN------RG-- 1156
            ||.|||.                    ...|.:      |.::.|.|......|.      ||
pombe   315 QPGAQQG--------------------EGEPFN------PANMFSNIFNLSGNPGDYAWGARGLD 353

  Fly  1157 ----ATLETIERNTLP--------HKYRRVRRPSETDEDAEKCAICLNLFEIENEVRRLPCMHLF 1209
                ..:|..:.:..|        .|.:..:.|.|..::..:|.||:.:|:|.::|.:|||.|.|
pombe   354 DIISQLMEQAQGHNAPAPAPEDVIAKMKVQKPPKELIDEEGECTICMEMFKINDDVIQLPCKHYF 418

  Fly  1210 HTDCVDQWLVTNKHCPICRVDIET---------------HMPNDALPPSSSGVPD 1249
            |.:|:..||..|..|.|||..::.               |.|::...||:|...|
pombe   419 HENCIKPWLRVNGTCAICRAPVDPNSQQRNNTSTDSANGHNPSNHANPSTSTTND 473

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6923	NP_001262484.1	zf-rbx1	<1185..1228	CDD:289448	18/42 (43%)
CG6923	NP_001262484.1	zf-RING_2	1187..1228	CDD:290367	18/40 (45%)
SPAP32A8.03c	NP_594179.1	HypA	<1..34	CDD:302785
SPAP32A8.03c	NP_594179.1	zf-RING_2	394..437	CDD:290367	18/42 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910