Protein Alignment CG6923 and toe-4

DIOPT Version :9

• Sequence 1: NP_001262484.1
• Gene: CG6923 / 41420
• FlyBaseID: FBgn0037944
• Length: 1265
• Species: Drosophila melanogaster
• Sequence 2: NP_493231.1
• Gene: toe-4 / 173144
• WormBaseID: WBGene00012194
• Length: 489
• Species: Caenorhabditis elegans
• Alignment Length: 590
• Identity: 123/590 - (20%)
• Similarity: 186/590 - (31%)
• Gaps: 209/590 - (35%)

  Fly   704 PRCSNMDPQRYFLPINESSMWMPGHPAPPPPPPPMPPILLPDNSSTEAYLRHQQRNLTST---PS 765
            |.|  |:||....|.:......|.....|.......|: :.:..||...:|.::|.....   |.
 Worm    37 PFC--MNPQLQTHPYDRQPTTAPRLQMMPRRDQTQNPV-IAELMSTVTRVRDRKRQRDEEAMYPR 98

  Fly   766 SSSSEQTSTQ--------------QSRHRR------SSPANVYHRYHPYYYAITTLPTVVESDYP 810
            .|...||.|:              ..|.||      ||...:               |...|...
 Worm    99 RSVGLQTDTEDVSEVLDGGTRISDMKRVRREELLDQSSLDGI---------------TFETSGTN 148

  Fly   811 PSLQPHPHPHPHFQPSQGGSSRSSLSGALNAAAVAATAAAVQAQTFSDLLSQAHNEGRAAALEGN 875
            .|.:||         ||..:|.||   :|.:.:.::::...:|...:..:.||....|      .
 Worm   149 TSDEPH---------SQIITSNSS---SLPSTSASSSSDRPRAMRSNQEMRQARRARR------Q 195

  Fly   876 RTPPHTMVHAQHQQR-QSINPPAPGVASNANLAAAVSPPPPLEMYSGRSTIPHC--GSPPFSVRR 937
            |...|.....|.:.| |.|..|.||...|                        |  |.|
 Worm   196 RQTQHESQRMQLEHRLQQITGPVPGSEHN------------------------CMTGCP------ 230

  Fly   938 SEAAYSNRQHYQPQPHQGHQAPQNQMHAHIHPPHRASAIVATSLTPAPPYPVHQNLWYRQQSMQE 1002
                     |...|..|.||.|...:..:..||...:...:.|.|.||               ..
 Worm   231 ---------HLHQQQQQQHQQPLLHIQLNPIPPQPQTGPNSVSPTIAP---------------GA 271

  Fly  1003 MHRRHMTPTPIDLSSNAPLLTSTLRNGYLHSICSCVHARNGPVSSLDPAYYPPYDAAPAAAA--- 1064
            |.|.|      .|:|..|..:..|...|             ||..:.|........|.||||
 Worm   272 MLRAH------PLASTFPYFSLPLTQNY-------------PVMMVLPMAAVAQQHAAAAAAVVA 317

  Fly  1065 ------------PPPSPQQQSPATSGSGNSSVAAQASMRHLQLQPQQQP---QAQQSPPVMQHMQ 1114
                        |||.|...:|                  :.::||..|   .|.::.|:..|..
 Worm   318 VAAAAAVPQPPPPPPQPTLHAP------------------VPIRPQNNPYNLYAFRNSPINVHAP 364

  Fly  1115 RQRAIHHHMF-----------------HHHYSPLHLEIGLAPLSLGSRILIAPSRPNRGATLETI 1162
            .....:..:|                 ||.:..|.|::.:                  ||:...|
 Worm   365 GYVGEYVELFRSQQFLFPTSERYGIDRHHMFGGLDLDLPV------------------GASKVEI 411

  Fly  1163 ERNTLPHKYRRVRRPSETDEDAEKCAICLNLFEIENEVRRLPCMHLFHTDCVDQWLVTNKHCPIC 1227
            :..|:|..|   .:.::.:||.:.|.:||:.||....:::|.|.|:||.:|:.:||..||.||:|
 Worm   412 DTFTIPTVY---AKKTDGEEDEDTCTVCLSSFEDGESIQKLRCNHVFHPECIYKWLDINKRCPMC 473

  Fly  1228 RVDIE 1232
            |.:|:
 Worm   474 REEID 478

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6923	NP_001262484.1	zf-rbx1	<1185..1228	CDD:289448	17/42 (40%)
		zf-RING_2	1187..1228	CDD:290367	17/40 (43%)
toe-4	NP_493231.1	RING-H2_RNF111_like	431..475	CDD:319388	18/43 (42%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162251
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BBW1
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003192
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1977
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.860