Protein Alignment CG6923 and C18orf25

DIOPT Version :9

• Sequence 1: NP_001262484.1
• Gene: CG6923 / 41420
• FlyBaseID: FBgn0037944
• Length: 1265
• Species: Drosophila melanogaster
• Sequence 2: NP_659492.1
• Gene: C18orf25 / 147339
• HGNCID: 28172
• Length: 404
• Species: Homo sapiens
• Alignment Length: 423
• Identity: 94/423 - (22%)
• Similarity: 141/423 - (33%)
• Gaps: 85/423 - (20%)

  Fly   104 RCESMVASSSRYADSTQNQSHSEAQFLEQPSS-STAAIANPPAVHSIPRPKRKKTEPLTMEPESD 167
            :.|.::.|.:....|.|..:..|...:|..|. ....:|:...:.|:|        .|.||...|
Human     9 KVEELIESEAPPKASEQETAKEEDGSVELESQVQKDGVADSTVISSMP--------CLLMELRRD 65

  Fly   168 NDGDAVVASVSGTWPAGAIEEHAMDSTAVVYEVPSSS-LQLSNSSFETAPSAVNAYDDVTSSASD 231
            : .::.:||.....|          :|..|||..||: ..||.||     |...|..|..|||.:
Human    66 S-SESQLASTESDKP----------TTGRVYESDSSNHCMLSPSS-----SGHLADSDTLSSAEE 114

  Fly   232 TEHGQFAHTRTTNTTTTTSAVQAHKKKASRSNNASNTSSRAVDTDATPSTSAQSR----KRQMSQ 292
            .|..| |.|......:..|.... .:|:.||.:.|.||:.|...:...|.....|    |...||
Human   115 NEPSQ-AETAVEGDPSGVSGATV-GRKSRRSRSESETSTMAAKKNRQSSDKQNGRVAKVKGHRSQ 177

  Fly   293 FSYRKSRVLEPENE---------------------------SSDD-----GWDLRVHNPVPPIEP 325
            ....:.|:|..:.|                           ||||     |....:...:|...|
Human   178 KHKERIRLLRQKREAAARKKYNLLQDSSTSDSDLTCDSSTSSSDDDEEVSGSSKTITAEIPDGPP 242

  Fly   326 TVTIIRGSRGSDEAEIGHTDH--------NYYNSRCAVAGAPPDSTYIRSASCSTATHTTRSVDY 382
            .|.....|..:.:.|:.:.|:        .:.||   |.|....:|:..|............:|.
Human   243 VVAHYDMSDTNSDPEVVNVDNLLAAAVVQEHSNS---VGGQDTGATWRTSGLLEELNAEAGHLDP 304

  Fly   383 GSRIGRRSAATGSP------STSSDQEQEQQQRQQQEEIIHEERRHQQSPGQPMH---SMYGVPG 438
            |.....:::|..:|      ..|||.|.|....|:....:|......||.....|   :.| |..
Human   305 GFLASDKTSAGNAPLNEEINIASSDSEVEIVGVQEHARCVHPRGGVIQSVSSWKHGSGTQY-VST 368

  Fly   439 ESRMSWSRARPSDDSVPPRKHARMELPGRSRSK 471
            ....||:...|......|.:...:.|...||.|
Human   369 RQTQSWTAVTPQQTWASPAEVVDLTLDEDSRRK 401

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6923	NP_001262484.1	zf-rbx1	<1185..1228	CDD:289448
		zf-RING_2	1187..1228	CDD:290367
C18orf25	NP_659492.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50		8/40 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..255		49/209 (23%)
		RNF111_N	<67..238	CDD:373730	44/187 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141572
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930