Protein Alignment CG6923 and rnf111

DIOPT Version :9

• Sequence 1: NP_001262484.1
• Gene: CG6923 / 41420
• FlyBaseID: FBgn0037944
• Length: 1265
• Species: Drosophila melanogaster
• Sequence 2: XP_005168980.1
• Gene: rnf111 / 100151141
• ZFINID: ZDB-GENE-070808-2
• Length: 1033
• Species: Danio rerio
• Alignment Length: 1311
• Identity: 272/1311 - (20%)
• Similarity: 397/1311 - (30%)
• Gaps: 513/1311 - (39%)

  Fly    66 TRSPPTYTAMVEPRREESSGFEGLARRCDKCSSLDGLCRCESMVASSSRYADS------------ 118
            |.:||.:..|:...|.|           |:.:....|..|.|..:||.|:.||
Zfish    99 TLTPPRHRPMLLETRSE-----------DERNPESSLSDCASSPSSSLRFGDSDTLSSDEDGMPM 152

  Fly   119 ---TQNQSHSEAQFLEQPSSSTAAIANPPAVHSIPRPKRKKTEP-LTMEPESDNDGDAVVAS--- 176
               .|.::|..|......||:..|:...|.   :.|.:..::.. ..:||:|::.....:.|
Zfish   153 TVRQQLKAHGAASTGSTGSSTGTAVGIRPL---LARTRASRSHKWARLEPDSNHVKRPCLGSRRP 214

  Fly   177 ------VSGTWPAGAIEEH------------------AMDSTAVVYEVPSSSLQLSNSSFETAPS 217
                  |.|  .||.:.:.                  |....|:::...|||.::  :|.:::||
Zfish   215 LHRKRFVKG--GAGGVTQRTPKQKERLLLQRKKREVIARKKYALLHSTSSSSEEM--TSDDSSPS 275

  Fly   218 AVNA----YDDVTSSASDTEHGQFAHTRTTNTTTTTSAVQAHKKKASRSNNASNTSS-------- 270
            :..|    |.||.||:|.......|............|..|....||...|.::|.|
Zfish   276 STEAEHELYVDVNSSSSQASTAAVASGVLDEDVVVIEATPAPAVPASEEINVTSTDSEVEIVTVG 340

  Fly   271 -----RAVDTDAT----PSTSAQSRKRQMSQFSYRKSRVLEPENESSDDGWDLRVHNPVPPIEPT 326
                 |:|.....    ||.| ||| .|..:..:|.|.|::|..:|:.:..||.|......:.||
Zfish   341 DAFRPRSVGGHGRMHWGPSCS-QSR-AQEGRGRHRLSTVIQPLRQSAGEVVDLTVDEDDLSVVPT 403

  Fly   327 VTIIRGSRGSDEAEIGHTDHNYYNSRCAVAGAPPDSTYIRSASCSTAT--HTTRSVDYGSRIGRR 389
            .     |..:....:..:..:  :||.|...|.|......|:|||.|.  .|..:..:|. :.|
Zfish   404 T-----SDSTHPQPVSSSSSS--SSRNACTSASPQEGPGPSSSCSAAAPDSTLAAQSHGG-VPR- 459

  Fly   390 SAATGSPSTSSDQEQEQQQRQQQEEIIHEERRHQQSPGQPMHSMYGVPGESRMSWS-------RA 447
               :|:.:|::.:::.::....:...:...|.....   |.||....|....:|..       ::
Zfish   460 ---SGTTNTTATEDESRRSLLGENGGVAMPRLPSCC---PQHSPCSGPSSGHLSMGHTHSGCMQS 518

  Fly   448 RPSDDSVPPRKHARMELPGRSRSKLSSTNFNSFYPGRRGHRTFAEQGNSSGQHHVRFPPSSTPNS 512
            ..:..|.||:       ||...|...|.:|:.                   .||....|||....
Zfish   519 GATQQSGPPQ-------PGSQHSHTHSHHFHH-------------------HHHTAPVPSSLAYQ 557

  Fly   513 NGPCVITYVGRPRDSQPAADLNLPSTSTGRRGSHETRADSVVLTAPDLQLDDWSSDDDDDDVVFV 577
            ...|.:        .:|.|   :|:...|....:..
Zfish   558 ESSCPL--------ERPTA---MPAPCGGVSNQYHD----------------------------- 582

  Fly   578 HSTREPILSIDLTSDDDGLANDTQLQRDRDRGRERERERARDREPYRNDTQPNPEDPNEDRRTMY 642
                :..|.:||:|.
Zfish   583 ----QQTLPVDLSSS-------------------------------------------------- 593

  Fly   643 DCAYTFPYARRTDRRTEANNEGTSAFAFYSGALADRAAISDHNYSYELDQLMDPGPGNFYPPRCS 707
                    |.|:...:.....|||||        |...               ||..:..|...|
Zfish   594 --------AVRSSGSSSTGFHGTSAF--------DPCC---------------PGSASRPPVYVS 627

  Fly   708 NMDPQRYFLPINESSMWMPGHPAPPPPPPPM----PPILLPDNSSTEAYLRHQQRNLTSTPSSSS 768
            ...|......:.:|  :.|...|.|.|.||.    ...:.|...|....|.||        ||||
Zfish   628 QAAPGPSQQTVADS--FSPTIVAQPQPQPPQLSSCRHYMHPTYGSLSRPLHHQ--------SSSS 682

  Fly   769 SEQTSTQQSRHRRSSPANVYHRYHPYYYAITTLPT-----VVESDYPPSLQPHPHPHPHFQPSQG 828
            ...:.:.....::..|...|...||.....|.|||     .|.:..||||..|
Zfish   683 CPHSHSNAPPPQQPPPQGDYVIPHPVLPFHTPLPTHAPGHTVPTAPPPSLPSH------------ 735

  Fly   829 GSSRSSLSGALNAAAVAATAAAVQAQTFSDLLSQAHNEGRAAALEGNRTPPHTMVHAQHQQRQSI 893
                                               |..|.:|.|..:..|.|..:  ||.
Zfish   736 -----------------------------------HLPGSSAPLPQHLPPEHQAL--QHH----- 758

  Fly   894 NPPAPGVASNANLAAAVSPPPPLEMYSGRSTIPHCGSPPFSV---------------RRSEAAYS 943
                                           :|..|  |.||               ||....:.
Zfish   759 -------------------------------LPVLG--PNSVQRLHHHDLLQRMEVQRRRMMQHP 790

  Fly   944 NRQHYQPQPHQGHQAPQNQMHA-HIHPPHRASAIVATSLTPAPPYPVHQNLWYRQQSMQEMHRRH 1007
            .|.|.:|.||. |:...|..|. |||.|                           |:|..:.|:.
Zfish   791 TRAHERPPPHP-HRMHPNYGHGHHIHVP---------------------------QTMSSLPRQS 827

  Fly  1008 MTPTPIDLSSNAPLLTSTLRNGYLHSICSCVHARNGPVSSLDPAYYPPYDAAPAAAAPPPSPQQQ 1072
            ...|..:|...|.:..:...:|:||.     |.         |.|:||             |:
Zfish   828 DQRTTWELGIEAGVTVAPYPSGHLHP-----HL---------PHYHPP-------------PR-- 863

  Fly  1073 SPATSGSGNSSVAAQASMRHLQLQPQQQPQAQQSPPV-MQHMQRQRAIHHHM-FHHHYSP-LHLE 1134
                             :.|.   |.|.......|.| ..|:   |.|...| |...|.. ||||
Zfish   864 -----------------LHHF---PIQLMHTGSMPEVTYPHI---RYISSRMTFGRTYEDLLHLE 905

  Fly  1135 IGLAPLSLGSRILIAPSRPNRGATLETIERNTLPHKYRR--VRRPSE------------------ 1179
            ..|..:             ||||:..||||.|.||||::  |.|.:|
Zfish   906 ERLGTV-------------NRGASQGTIERCTYPHKYKKKVVERDTEEQLAPEAWASVGKKMHST 957

  Fly  1180 ---------------TDEDA-EKCAICLNLFEIENEVRRLPCMHLFHTDCVDQWLVTNKHCPICR 1228
                           .:||. |||.|||::.|...:|||||||||||..||||||:|||.|||||
Zfish   958 SNSRKLHGKQEEEEGAEEDTEEKCTICLSILEEGEDVRRLPCMHLFHQLCVDQWLLTNKKCPICR 1022

  Fly  1229 VDIETHMPNDA 1239
            ||||..:.:::
Zfish  1023 VDIEAQLSSES 1033

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6923	NP_001262484.1	zf-rbx1	<1185..1228	CDD:289448	30/42 (71%)
		zf-RING_2	1187..1228	CDD:290367	28/40 (70%)
rnf111	XP_005168980.1	RNF111_N	1..284	CDD:291949	40/202 (20%)
		zf-RING_2	981..1022	CDD:290367	28/40 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574551
Domainoid	1	1.000	79	1.000	Domainoid score	I8608
eggNOG	1	0.900	-	-		E33208_3BBW1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	133	1.000	Inparanoid score	I4580
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm25205
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1977
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	9	8.820