DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG6923 and rnf126

DIOPT Version :9

Sequence 1:	NP_001262484.1	Gene:	CG6923 / 41420	FlyBaseID:	FBgn0037944	Length:	1265	Species:	Drosophila melanogaster
Sequence 2:	NP_001076486.1	Gene:	rnf126 / 100009648	ZFINID:	ZDB-GENE-070209-292	Length:	309	Species:	Danio rerio

Alignment Length:	210	Identity:	49/210 - (23%)
Similarity:	78/210 - (37%)	Gaps:	71/210 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly  1085 AAQASMRHLQLQPQQQPQAQQSPPVMQHMQRQRAIHHHMFHHHYSPLHLEIGLAPLSLGSRILIA 1149
            |.|...||:   |::|.|..:..|.::.:.:|                         |.:.|:..
Zfish   119 ARQPRGRHV---PRRQGQRHEGVPTLEGIIQQ-------------------------LVNGIIAP 155

  Fly  1150 PSRPNR-----------------GAT-LETIERNTLPHKYRRVRRPSETDEDAEK---------- 1186
            .:.||.                 ||. |:.|....| :::... .|...|:|..|
Zfish   156 TAMPNMAMGPWGMLHSNPMDYAWGANGLDAIITQLL-NQFENT-GPPPADKDKIKSLPTVQIKQE 218

  Fly  1187 -------CAICLNLFEIENEVRRLPCMHLFHTDCVDQWLVTNKHCPICRVDIETHMPNDAL-PPS 1243
                   |.:|...:.....||:|||.||||.||:..||..:..||:||..:...  |.|. ||.
Zfish   219 HVGAGLECPVCKEDYSAGENVRQLPCNHLFHNDCIVPWLEQHDTCPVCRKSLSGQ--NTATDPPG 281

  Fly  1244 SSGV---PDAANSAA 1255
            .||:   |.:::|::
Zfish   282 LSGMNFSPSSSSSSS 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG6923	NP_001262484.1	zf-rbx1	<1185..1228	CDD:289448	18/59 (31%)
CG6923	NP_001262484.1	zf-RING_2	1187..1228	CDD:290367	17/40 (43%)
rnf126	NP_001076486.1	zinc_ribbon_9	10..40	CDD:291067
rnf126	NP_001076486.1	zf-RING_2	225..267	CDD:290367	17/41 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1249953at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010