DRSC/TRiP Functional Genomics Resources

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Protein Alignment MAS1 and CCHa1-R

DIOPT Version :9

Sequence 1:NP_001353633.1 Gene:MAS1 / 4142 HGNCID:6899 Length:325 Species:Homo sapiens
Sequence 2:NP_611241.2 Gene:CCHa1-R / 37004 FlyBaseID:FBgn0050106 Length:499 Species:Drosophila melanogaster


Alignment Length:364 Identity:79/364 - (21%)
Similarity:147/364 - (40%) Gaps:81/364 - (22%)


- Green bases have known domain annotations that are detailed below.


Human     5 NVTSFVVEEPTNISTGRNASVGNAHRQIPIVHWVIMSISPVGFVENG-ILLWFLCFRMRRNPFTV 68
            |.:..|..|...:..||....    ..:||:..:|.   .||.:.|| :::.||..|..||....
  Fly    61 NFSELVTTETPYVPYGRRPET----YIVPILFALIF---VVGVLGNGTLIVVFLSVRQMRNVPNT 118

Human    69 YITHLSIADISLLF-CIFILSIDYALDY------ELSSGHYYTIVTLSVTFLFGYNTGLYLLTAI 126
            ||..|::||:.::. .:.:.|..|.::|      ..|...:...|::.|:        ::.|||:
  Fly   119 YILSLALADLLVIITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVS--------VFTLTAL 175

Human   127 SVERCLSVLYPI-WYRCH---RPKYQSALVCAL-LWALSCL---------------VTTMEYVMC 171
            |.:|..:::.|: .:..|   |...:..|..|: :|.|:.|               :.....|:|
  Fly   176 SGDRYFAIVDPLRKFHAHGGGRRATRMTLATAVSIWLLAILCGLPALIGSNLKHLGINEKSIVIC 240

Human   172 IDREEE---SHSRNDCRAVIIFIAILSFLVFTPLMLVSSTILVVKIRKNTWASHS---------- 223
            ....||   :::::        :.:|.|||:..:.||...:..|.|..:...|.|          
  Fly   241 YPYPEEWGINYAKS--------MVLLHFLVYYAIPLVVIAVFYVLIALHLMYSASVPGEIQGAVR 297

Human   224 -----SKLYIVIMVTIIIFLIFAMPMRLLYLLYYEYWSTFGN--------LHHISLLFSTINSSA 275
                 .|:.:.::..::||.|..:|..:.:|.:| :|.|..:        |..::...|..||.|
  Fly   298 QVRARRKVAVTVLAFVVIFGICFLPYHVFFLWFY-FWPTAQDDYNAFWHVLRIVAYCMSFANSCA 361

Human   276 NPFIYFFVGSSKKKRFKESLKVVLTRAFKDEMQPRRQKD 314
            ||...:||..:.:|.|.   :.:..|......:.|.|.|
  Fly   362 NPVALYFVSGAFRKHFN---RYLFCRGASGRRKKRGQHD 397

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
MAS1NP_001353633.1 7tmA_MrgprH 33..307 CDD:320238 71/327 (22%)
TM helix 1 34..60 CDD:320238 8/26 (31%)
TM helix 2 66..89 CDD:320238 5/23 (22%)
TM helix 3 107..135 CDD:320238 6/27 (22%)
TM helix 4 147..167 CDD:320238 5/35 (14%)
TM helix 5 192..217 CDD:320238 8/24 (33%)
TM helix 6 221..251 CDD:320238 8/44 (18%)
TM helix 7 259..284 CDD:320238 8/32 (25%)
CCHa1-RNP_611241.2 7tm_4 88..>188 CDD:304433 27/110 (25%)
7tm_1 98..364 CDD:278431 60/282 (21%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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