Protein Alignment CG14722 and JIP5

DIOPT Version :10

• Sequence 1: NP_650111.3
• Gene: CG14722 / 41419
• FlyBaseID: FBgn0037943
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_015495.2
• Gene: JIP5 / 856298
• SGDID: S000006373
• Length: 492
• Species: Saccharomyces cerevisiae
• Alignment Length: 491
• Identity: 89/491 - (18%)
• Similarity: 157/491 - (31%)
• Gaps: 175/491 - (35%)

  Fly    76 FDPNAADSDSDDSMLDEAGGV-TAGGATSAKK------RKDDDNPSGSNKQPEATFDLDEDDETD 133
            :||....|.     ||....: ||.....|||      |.|.|..:|..|    ..|::|..:..
Yeast    54 YDPAKLQSH-----LDRRRRIDTATTGKDAKKGVCPWIRLDIDLETGDLK----FVDIEEQQQQK 109

  Fly   134 ET--------------------VRAMI-------------------------AAIKKPRSSP--- 150
            :|                    ||||.                         ..:||...|.
Yeast   110 QTGKDEDLGVKTLWKTKRHKGSVRAMCFDSKGDNIFSVGSDNVLKKANTMTGKVVKKVNLSSLFN 174

  Fly   151 PEIKLEDFITDIC---FHP--------------DRDIIALATIIGDVHL---------------Y 183
            .|.|..|..|.:|   .||              :.:.:||:..|..:|.               |
Yeast   175 SEEKKNDKFTKLCASQTHPFILIGDESGNIHVINSENLALSNSIRSIHFGDSINDIFHFDKRSAY 239

  Fly   184 EYDNEANKLLRTIEVHSKACR-DVEFTEDGRFLLTCSKDKCVMVTDMETEKLKKLYETAHDDAIN 247
            ::.:.....|...:|..|..: :|...|||:.|::         .|.|.|.|...:  ...:..:
Yeast   240 KFISLGQTTLAYFDVRDKDAKPNVAGNEDGKILIS---------DDQEDEVLCGCF--VDPEVAD 293

  Fly   248 TLHVLNENLFASGDDAGTVKLWDLRTKNAIFELKELEDQITQLTTNEQSKLLLATSADGYLTTFN 312
            ||      |...|:  |.|.:|. ..||      :||||::::..::
Yeast   294 TL------LCGMGE--GIVTVWK-PNKN------DLEDQMSRIKISK------------------ 325

  Fly   313 ISARKMYVQSEPYEEELNC-MGVYRGDSKLVVGTSKGRLYTYNWGQFG------YHCDMYPGIKS 370
                         :|.::| :...:.|:.:..|.|.|.:|..| .:.|      .|.::     .
Yeast   326 -------------DESIDCIVPTLQDDNCVWCGCSNGNIYKVN-AKLGKVVEIRNHSEL-----D 371

  Fly   371 PISLMIPITDRIACVAGEDGNIRACHIAP---YRNLGVVGQHNMPIESLDVNASGELIASSSHNN 432
            .:| .:.:......|:|...||:...::.   ..|..|....:.|:...|.:.|.:    :|.::
Yeast   372 EVS-FVDLDFEYRVVSGGLENIKIWELSSDDVEENASVESDSDEPLSHSDEDLSDD----TSSDD 431

  Fly   433 DVRFWNVKYFEDFGDIKYNEKHNAYKEQRHNLPSSK 468
            :.....:...|...::..:.|.:..:|:..|..|.|
Yeast   432 ETTLVGLSKEELLDELDKDLKEDHQEEKESNSKSVK 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14722	NP_650111.3	WD40	156..438	CDD:475233	56/324 (17%)
		WD40 repeat	160..198	CDD:293791	10/69 (14%)
		WD40 repeat	203..239	CDD:293791	9/36 (25%)
		WD40 repeat	247..284	CDD:293791	9/36 (25%)
		WD40 repeat	287..354	CDD:293791	7/67 (10%)
		WD40 repeat	367..406	CDD:293791	6/41 (15%)
		WD40 repeat	413..437	CDD:293791	3/23 (13%)
JIP5	NP_015495.2	WD40 repeat	132..168	CDD:293791	6/35 (17%)
		WD40 repeat	184..219	CDD:293791	6/34 (18%)
		WD40 repeat	227..273	CDD:293791	8/45 (18%)
		WD40 repeat	281..322	CDD:293791	14/57 (25%)
		WD40 repeat	329..352	CDD:293791	5/22 (23%)