Protein Alignment CG14722 and LOC5668295

DIOPT Version :10

• Sequence 1: NP_650111.3
• Gene: CG14722 / 41419
• FlyBaseID: FBgn0037943
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: XP_001689008.2
• Gene: LOC5668295 / 5668295
• VectorBaseID: AGAMI1_006136
• Length: 484
• Species: Anopheles gambiae
• Alignment Length: 497
• Identity: 243/497 - (48%)
• Similarity: 333/497 - (67%)
• Gaps: 28/497 - (5%)

  Fly     6 NFKTP--SDEDELDDLDE-DMVVGVIA----EIE--QEVLNESDSDNDEYDLVDMGAPVPDNDGD 61
            ||::|  .|.|:.::.:| |:...::|    |:|  .|.|:|.:..:...:..||......:|.|
Mosquito     3 NFQSPYFRDSDDSEEEEEIDLAPYILAVRPDELEGLVEYLSEGEDVSAPAESFDMPNADESSDSD 67

  Fly    62 ISYEGNDSSSSDDSFDPNAADSDSDDSMLDEAGGVTAGGATSAKKRKDDDNPSGSNKQPEA---T 123
            .:||..|.|...||    :.|||||....::|......||..|    ...|..|:.::..|   .
Mosquito    68 DTYEVEDDSQMSDS----SLDSDSDGQAEEDAANGNKPGAAQA----STSNGEGTAEEAPARRVI 124

  Fly   124 FDLDEDDETDETVRAMIAAIKKPRSSPPEIKLEDFITDICFHPDRDIIALATIIGDVHLYEYDNE 188
            .|.|||.|.||.::|:|:.||||||.||:|:.|||:.|:.|||..||:|:.|.:|||.:|.|.|:
Mosquito   125 DDYDEDMEEDEVIKAIISEIKKPRSKPPDIQTEDFVVDLSFHPCEDILAVGTSVGDVLMYRYAND 189

  Fly   189 ANKLLRTIEVHSKACRDVEFTEDGRFLLTCSKDKCVMVTDMETEKLKKLYETAHDDAINTLHVLN 253
            ||.|..|.|:|:||.|.|||..||:.|::..:::.::|.|.||.|.|:.:|:|||:.:.::.||.
Mosquito   190 ANVLAATHELHTKAIRCVEFVPDGKSLISTGRERSIVVMDAETGKFKRFWESAHDEPVYSMTVLG 254

  Fly   254 ENLFASGDDAGTVKLWDLRTKNAIFELKELEDQITQLTTNE-QSKLLLATSADGYLTTFNISARK 317
            |:|||:|||.|.|||||:|.:||:|.|:.:||.::.|..|: |.|.||.||.||.|||.||:.||
Mosquito   255 EHLFATGDDDGEVKLWDVRERNAVFSLRPVEDFVSSLLANQHQQKYLLLTSGDGLLTTINIAQRK 319

  Fly   318 MYVQSEPYEEELNCMGVYRGDSKLVVGTSKGRLYTYNWGQFGYHCDMYPGIKSPISLMIPITDRI 382
            ||||||||||||||||:::.:||||||||||..||||||||.||||.:.|..:..:.|:|||::|
Mosquito   320 MYVQSEPYEEELNCMGMFKRESKLVVGTSKGNYYTYNWGQFAYHCDAFTGPSASANRMVPITEQI 384

  Fly   383 ACVAGEDGNIRACHIAPYRNLGVVGQHNMPIESLDVNASGELIASSSHNNDVRFWNVKYFEDFGD 447
            |.:|||||.:||.|:.|.|.||:||||:|.:::||::.||||||||||:||||||||||||||..
Mosquito   385 AVMAGEDGILRAMHMVPGRVLGIVGQHSMAVDTLDISGSGELIASSSHDNDVRFWNVKYFEDFDG 449

  Fly   448 IKYNEKHNAYKEQRHNLPSSKCSNASDFFSDLTKENADGDDD 489
            ||||.|.:. :..|||||||:.:||.|||:.|      |||:
Mosquito   450 IKYNSKPDK-RMLRHNLPSSQRTNAKDFFAGL------GDDE 484

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14722	NP_650111.3	WD40	156..438	CDD:475233	160/282 (57%)
		WD40 repeat	160..198	CDD:293791	18/37 (49%)
		WD40 repeat	203..239	CDD:293791	13/35 (37%)
		WD40 repeat	247..284	CDD:293791	20/36 (56%)
		WD40 repeat	287..354	CDD:293791	45/67 (67%)
		WD40 repeat	367..406	CDD:293791	19/38 (50%)
		WD40 repeat	413..437	CDD:293791	16/23 (70%)
LOC5668295	XP_001689008.2	None