Protein Alignment CG14722 and wdr55

DIOPT Version :10

• Sequence 1: NP_650111.3
• Gene: CG14722 / 41419
• FlyBaseID: FBgn0037943
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_001342873.1
• Gene: wdr55 / 3361484
• PomBaseID: SPAC1A6.02
• Length: 361
• Species: Schizosaccharomyces pombe
• Alignment Length: 368
• Identity: 101/368 - (27%)
• Similarity: 166/368 - (45%)
• Gaps: 48/368 - (13%)

  Fly   141 AAIKKPRSSPPEIKLEDFITDI-CFHPDRDIIALATIIGDVHLYEYDNEANKLLR--TIEVHSKA 202
            ||||:        |.|:.|.|: ||..::.::..:.  |.|..|:||.....|:.  :.:.|.|:
pombe     7 AAIKQ--------KFENEIFDLACFGENQVLLGFSN--GRVSSYQYDVAQISLVEQWSTKRHKKS 61

  Fly   203 CRDVEFTEDGRFLLTCSKDKCVMVTDMETEKLKKLYETAHDDAINTLHVL----NENLFASGDDA 263
            ||::...|.|...::...|..:.:.|..|.::...:....:..|:...|:    |:.:||:|||.
pombe    62 CRNISVNESGTEFISVGSDGVLKIADTSTGRVSSKWIVDKNKEISPYSVVQWIENDMVFATGDDN 126

  Fly   264 GTVKLWDLRTKNAIFEL-KELEDQITQLTTNEQSKLLLATSADGYLTTFNISARKMYVQSEPYEE 327
            |.|.:||.||:..|... .:..|.|:.::..|: :..:|||.||.|:..:....|..:.||..:|
pombe   127 GCVSVWDKRTEGGIIHTHNDHIDYISSISPFEE-RYFVATSGDGVLSVIDARNFKKPILSEEQDE 190

  Fly   328 ELNCMGVYRGD----SKLVVGTSKGRLYTYNWGQFGYHCDMYPGIKSPI---SLMIPITDRI--- 382
            |:.| |.:..|    .|..|||:.|.:..:..|.:|.|.|.   |.|||   ...|....|.
pombe   191 EMTC-GAFTRDQHSKKKFAVGTASGVITLFTKGDWGDHTDR---ILSPIRSHDFSIETITRADSD 251

  Fly   383 -ACVAGEDGNIRACHIAPYRNLGVVGQHN--MPIESLDVNASGELIASSSHNNDVRFWNVKYFED 444
             ..|.|.||.||..||.|.:...::|||:  ..::::||...|..:.|.| ..::.||.|
pombe   252 SLYVGGSDGCIRLLHILPNKYERIIGQHSSRSTVDAVDVTTEGNFLVSCS-GTELAFWPV----- 310

  Fly   445 FGDIKYNEKHNAYKEQRHNLPSSKCSNASDFFSDLTKENADGD 487
                  ::|.........||.|.:.|::...||...|:...|:
pombe   311 ------DQKEGDESSSSDNLDSDEDSSSDSEFSSPKKKKKVGN 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14722	NP_650111.3	WD40	156..438	CDD:475233	85/302 (28%)
		WD40 repeat	160..198	CDD:293791	9/40 (23%)
		WD40 repeat	203..239	CDD:293791	7/35 (20%)
		WD40 repeat	247..284	CDD:293791	14/41 (34%)
		WD40 repeat	287..354	CDD:293791	21/70 (30%)
		WD40 repeat	367..406	CDD:293791	15/45 (33%)
		WD40 repeat	413..437	CDD:293791	5/23 (22%)
wdr55	NP_001342873.1	WD40 repeat	17..54	CDD:293791	10/38 (26%)
		WD40	<56..311	CDD:441893	76/271 (28%)
		WD40 repeat	64..99	CDD:293791	5/34 (15%)
		WD40 repeat	109..146	CDD:293791	14/36 (39%)
		WD40 repeat	151..185	CDD:293791	9/34 (26%)
		WD40 repeat	193..239	CDD:293791	16/49 (33%)
		WD40 repeat	242..278	CDD:293791	11/35 (31%)