Protein Alignment CG14722 and Wdr55

DIOPT Version :10

• Sequence 1: NP_650111.3
• Gene: CG14722 / 41419
• FlyBaseID: FBgn0037943
• Length: 498
• Species: Drosophila melanogaster
• Sequence 2: NP_001017932.1
• Gene: Wdr55 / 307494
• RGDID: 1305640
• Length: 384
• Species: Rattus norvegicus
• Alignment Length: 385
• Identity: 124/385 - (32%)
• Similarity: 202/385 - (52%)
• Gaps: 34/385 - (8%)

  Fly   125 DLDEDDETDETVRAMIAAIKKPRSSPPEIKLEDFITDICFHPDRDIIALATIIGDVHLYEY---D 186
            |.:.:::.|.|     .|..:.|.:|.:|.||...:.:.|||.||::|...:.|||.::.|   :
  Rat    12 DSNNEEDLDST-----KAAPRIRDTPEDIVLEAPASGLAFHPTRDLLAAGDVDGDVFVFAYSCQE 71

  Fly   187 NEANKLLRTIEVHSKACRDVEFTEDGRFLLTCSKDKCVMVTDMETEKLKKLYETAHDDAINTLHV 251
            .|..:|..:.. |.|:||.|.|:|||:.|:|.||||.:.|.|:|..:|::....||...||:|.:
  Rat    72 GETKELWSSGH-HLKSCRAVVFSEDGQKLVTVSKDKAIHVLDVEQGQLERRISKAHSAPINSLLL 135

  Fly   252 LNENLFASGDDAGTVKLWDLRTKNAIFELKELEDQITQLTTNEQSKLLLATSADGYLTTFNISAR 316
            ::||:..:|||.|.::|||.|.:..:.::::.|:.|..:..:...||||..|.||.|..|||..|
  Rat   136 VDENVLVTGDDTGGIRLWDQRKEGPLMDMRQHEEYIADMALDPAKKLLLTASGDGCLGVFNIKRR 200

  Fly   317 KMYVQSEPYEEELNCMGVYRGDSKLVVGTSKGRLYTYNWGQFGYHCDMYPGIKSPISLMIPITDR 381
            :..:.|||...:|..:.:.:...|:..|:|:|.:|.:||..||...|.:......|..|:|:|:.
  Rat   201 RFELLSEPQSGDLTSVALMKYGKKVACGSSEGTIYLFNWNGFGATSDRFALRAESIDCMVPVTEN 265

  Fly   382 IACVAGEDGNIRACHIAPYRNLGVVGQH-NMPIESLDVNASGELIASSSHNNDVRFWNVKYFED- 444
            :.|....||.|||.:|.|.|.:|.|||| ..|:|.|.::..|..:|||.|:..::||::.....
  Rat   266 LLCTGSTDGIIRAVNILPNRVVGTVGQHAGEPVEELALSHCGHFLASSGHDQRLKFWDMTQLRTV 330

  Fly   445 -FGDIKYNEKHNAYKEQRHNLP----SSKCSNASDFFSDLTKE----------NADGDDD 489
             ..|.:..:|...        |    |||..:..|||:.|.::          :.:.|||
  Rat   331 VVDDYRRRKKKGG--------PLRALSSKAWSTDDFFAGLREDEEEAKAPEEVSGESDDD 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14722	NP_650111.3	WD40	156..438	CDD:475233	102/285 (36%)
		WD40 repeat	160..198	CDD:293791	12/40 (30%)
		WD40 repeat	203..239	CDD:293791	17/35 (49%)
		WD40 repeat	247..284	CDD:293791	12/36 (33%)
		WD40 repeat	287..354	CDD:293791	22/66 (33%)
		WD40 repeat	367..406	CDD:293791	14/38 (37%)
		WD40 repeat	413..437	CDD:293791	7/23 (30%)
Wdr55	NP_001017932.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..33		5/25 (20%)
		WD 1	36..75		13/38 (34%)
		WD40	39..332	CDD:441893	102/293 (35%)
		WD40 repeat	42..81	CDD:293791	12/38 (32%)
		WD 2	82..121		19/39 (49%)
		WD40 repeat	88..125	CDD:293791	16/36 (44%)
		WD 3	125..163		15/37 (41%)
		WD40 repeat	130..165	CDD:293791	13/34 (38%)
		WD 4	166..205		14/38 (37%)
		WD40 repeat	172..206	CDD:293791	12/33 (36%)
		WD 5	208..247		11/38 (29%)
		WD40 repeat	213..250	CDD:293791	11/36 (31%)
		WD 6	250..289		13/38 (34%)
		WD40 repeat	258..295	CDD:293791	17/36 (47%)
		WD 7	293..332		11/38 (29%)
		WD40 repeat	302..322	CDD:293791	5/19 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	362..384		4/21 (19%)