DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14721 and TPK1

DIOPT Version :9

Sequence 1:	NP_650110.3	Gene:	CG14721 / 41417	FlyBaseID:	FBgn0037942	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_001321568.1	Gene:	TPK1 / 839303	AraportID:	AT1G02880	Length:	273	Species:	Arabidopsis thaliana

Alignment Length:	293	Identity:	81/293 - (27%)
Similarity:	133/293 - (45%)	Gaps:	56/293 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 HSATHRFLCTKTTIGFRQQMDHTIPPKEYKWTPGNLINENFKLGDHGHVCVVLNRQIQVPAHVVK 116
            ||::....|.:|:.|.|                              :..||||:.:   .....
plant     9 HSSSFLLPCDETSTGTR------------------------------YALVVLNQSL---PRFTP 40

  Fly   117 LLWKNAAVRCAVDGGSNHWRDFVV-------AQAMSKKANGSAPTTPLEPLDVITGDFDSITEET 174
            |||::|.:|...|||:|...|.:.       |.|:..::|......|    |||.||.|||..:.
plant    41 LLWEHAKLRLCADGGANRIYDELPLFFPNEDALAIRNRSNFLKLYKP----DVIKGDMDSIRRDV 101

  Fly   175 VDFF-----KTTPKVHTPDQDATDFTKAMAVLQPVMTQRKIQ--DVVVFHDTSGRLDQVMANLNT 232
            :||:     |...:.|  |||.||..|.:..::.....::..  .::......||.|....|||.
plant   102 LDFYINLGTKVIDESH--DQDTTDLDKCILYIRHSTLNQETSGLQILATGALGGRFDHEAGNLNV 164

  Fly   233 LYKSQKDNCNVFLLSGDSVTWLLRPGKHTIQVPVDLVTSQRWCSLMPVGSSAHNVTTTGLKWNLY 297
            ||:  ..:..:.|||.|.:..|| |..|..::.:........|.|:|:|:.:...||:||:|:|.
plant   165 LYR--YPDTRIVLLSDDCLIQLL-PKTHRHEIHIQSSLEGPHCGLIPIGTPSAKTTTSGLQWDLS 226

  Fly   298 HAQLEFGGMVSTSNTYATEFVQVETDANLIWSM 330
            :.::.|||::||||....|.:.||:|::|:|::
plant   227 NTEMRFGGLISTSNLVKEEKITVESDSDLLWTI 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14721	NP_650110.3	TPK	100..328	CDD:153431	74/241 (31%)
CG14721	NP_650110.3	thi_PPkinase	101..330	CDD:273588	75/242 (31%)
TPK1	NP_001321568.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	61	1.000	Domainoid score	I3820
eggNOG	1	0.900	-	-		E1_COG1564
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	113	1.000	Inparanoid score	I2048
OMA	1	1.010	-	-		QHG54595
OrthoDB	1	1.010	-	-		D1428589at2759
OrthoFinder	1	1.000	-	-		FOG0005247
OrthoInspector	1	1.000	-	-		otm2991
orthoMCL	1	0.900	-	-		OOG6_101973
Panther	1	1.100	-	-	LDO	PTHR13622
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3766
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.930