DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14721 and tpk1

DIOPT Version :9

Sequence 1:	NP_650110.3	Gene:	CG14721 / 41417	FlyBaseID:	FBgn0037942	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	XP_012820234.2	Gene:	tpk1 / 549924	XenbaseID:	XB-GENE-958035	Length:	250	Species:	Xenopus tropicalis

Alignment Length:	275	Identity:	104/275 - (37%)
Similarity:	147/275 - (53%)	Gaps:	32/275 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    68 RQQMDHTIPPKEYKWTPGNLINENFKLGDHGHVCVVLNRQIQVPAHVVKLLWKNAAVRCAVDGGS 132
            |.:|::|..|.|.....|||          .:..::||:.:.  ..::..||:.|..:...|||:
Frog     2 RLKMENTFTPLECLQPAGNL----------KYCLIILNQPLD--KSLLIHLWETAIFKACADGGA 54

  Fly   133 NHWRDFVVAQAMSKKANGSAPTTPLEPLDVITGDFDSITEETVDFFKT--TPKVHTPDQDATDFT 195
            |.     :.|||....:...|       |.|:||||||..|...|:|.  ...:.|||||.||||
Frog    55 NR-----LYQAMEGSQDRYLP-------DFISGDFDSIKPEIKTFYKEQGCELIQTPDQDFTDFT 107

  Fly   196 KAMAVLQPVMTQRKIQ-DV-VVFHDTSGRLDQVMANLNTLYKSQKDNCNVFLLSGDSVTWLLRPG 258
            |.:.:||..:.|..:: || ||.....||.||:||::.|||.:... ..|.::...|:..||:||
Frog   108 KCLKILQDKIRQSNVEMDVIVVLGGLGGRFDQIMASVETLYHAVTP-LPVIIMQDTSLICLLKPG 171

  Fly   259 KHTIQVPVDLVTSQRWCSLMPVGSSAHNVTTTGLKWNLYHAQLEFGGMVSTSNTY-ATEFVQVET 322
            ||.:.|...  ...:||.|:||||:.::||||||||||....|:||.:|||||:| .|..|.|||
Frog   172 KHILHVATG--KEAKWCGLIPVGSACNSVTTTGLKWNLSAGVLKFGTLVSTSNSYDGTGVVTVET 234

  Fly   323 DANLIWSMGAYEFED 337
            |..|:|:||..:..|
Frog   235 DNPLVWTMGIKKMND 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14721	NP_650110.3	TPK	100..328	CDD:153431	92/232 (40%)
CG14721	NP_650110.3	thi_PPkinase	101..330	CDD:273588	93/233 (40%)
tpk1	XP_012820234.2	PLN02714	25..244	CDD:178316	94/235 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I9029
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6960
Inparanoid	1	1.050	156	1.000	Inparanoid score	I4199
OMA	1	1.010	-	-		QHG54595
OrthoDB	1	1.010	-	-		D1428589at2759
OrthoFinder	1	1.000	-	-		FOG0005247
OrthoInspector	1	1.000	-	-		oto105008
Panther	1	1.100	-	-	LDO	PTHR13622
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1532
SonicParanoid	1	1.000	-	-		X3766
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110