DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14721 and tpk1

DIOPT Version :9

Sequence 1:	NP_650110.3	Gene:	CG14721 / 41417	FlyBaseID:	FBgn0037942	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_001006074.1	Gene:	tpk1 / 450054	ZFINID:	ZDB-GENE-041010-176	Length:	257	Species:	Danio rerio

Alignment Length:	245	Identity:	91/245 - (37%)
Similarity:	129/245 - (52%)	Gaps:	29/245 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 VC-VVLNRQIQVPAHVVKLLWKNAAVRCAVDGGSNHWRDFVVAQAMSKKANGSAPTTPLEPLDVI 163
            :| |:||:.:.  .....:||..|.:|...|||:||     :.:....:.....|       |.|
Zfish    18 ICLVILNQPLD--ERYFHVLWSKAQIRACADGGANH-----LYRLTEGRRESFLP-------DYI 68

  Fly   164 TGDFDSITEETVDFF--KTTPKVHTPDQDATDFTKAMAVLQPVMTQRKIQ--DVVVFHDTSGRLD 224
            .||||||..|...|:  |....:.|||||.|||||.:|::...:..:|:|  .:|......||.|
Zfish    69 NGDFDSILPEVKAFYAGKNCKLMETPDQDLTDFTKCLAIMLEEIKAKKLQIDSIVTLGGLGGRFD 133

  Fly   225 QVMANLNTLYKSQK-DNCNVFLLSGDSVTWLLRPGKHTIQVPVDLVTSQRWCSLMPVGSSAHNVT 288
            |.||...||:.:|| .:..|.::...|:.:||:.|:|. |:.|:.....:||||:||||.. ..|
Zfish   134 QTMATEETLFHAQKMTDLPVVVIQDSSLAFLLKEGRHH-QLNVNTGMEGKWCSLVPVGSPC-LTT 196

  Fly   289 TTGLKWNLYHAQLEFGGMVSTSNTY-------ATEFVQVETDANLIWSMG 331
            |:||||||.:..|.||.:|||||||       ..:.|.:.||..|:||||
Zfish   197 TSGLKWNLDNQVLAFGQLVSTSNTYEDHDPKDCRKPVTITTDNPLLWSMG 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14721	NP_650110.3	TPK	100..328	CDD:153431	87/240 (36%)
CG14721	NP_650110.3	thi_PPkinase	101..330	CDD:273588	88/241 (37%)
tpk1	NP_001006074.1	TPK	19..243	CDD:153431	87/239 (36%)
tpk1	NP_001006074.1	PLN02714	20..247	CDD:178316	90/243 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170580499
Domainoid	1	1.000	75	1.000	Domainoid score	I9061
eggNOG	1	0.900	-	-		E1_COG1564
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6960
Inparanoid	1	1.050	138	1.000	Inparanoid score	I4518
OMA	1	1.010	-	-		QHG54595
OrthoDB	1	1.010	-	-		D1428589at2759
OrthoFinder	1	1.000	-	-		FOG0005247
OrthoInspector	1	1.000	-	-		oto38837
orthoMCL	1	0.900	-	-		OOG6_101973
Panther	1	1.100	-	-	LDO	PTHR13622
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1532
SonicParanoid	1	1.000	-	-		X3766
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800