DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14721 and tpk-1

DIOPT Version :9

Sequence 1:	NP_650110.3	Gene:	CG14721 / 41417	FlyBaseID:	FBgn0037942	Length:	345	Species:	Drosophila melanogaster
Sequence 2:	NP_001023024.1	Gene:	tpk-1 / 176258	WormBaseID:	WBGene00014027	Length:	243	Species:	Caenorhabditis elegans

Alignment Length:	242	Identity:	69/242 - (28%)
Similarity:	123/242 - (50%)	Gaps:	24/242 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 VCVVLNRQIQVPAHVVKLLWKNAAVRCAVDGGSNHWRDFVVAQAMSKKANGSAPTTPLEPLDVIT 164
            ||:.||.:....::..:.||..|..|.|.||..|        :.:.:|:....|       .:|.
Worm    18 VCIWLNGEPTAISNRAENLWNKAKYRVATDGAVN--------EILKRKSFVEWP-------HIIC 67

  Fly   165 GDFDSITEETVDFFKTTPKVHTPDQDATDFTKAM--AVLQPVMTQRKIQDVVVFHDTSGRLDQVM 227
            ||||||.:: :| .|....||.||||.||.:|::  .:.|..:|..:.:::||....:||.|..|
Worm    68 GDFDSINKQ-ID-TKNAKVVHLPDQDYTDLSKSVQWCLEQKTLTSWEFENIVVLGGLNGRFDHTM 130

  Fly   228 ANLNTLYKSQKDNCNVFLLSGDSVTWLLRPGKHTIQVPVDLVTSQRWCSLMPVGSSAHNVTTTGL 292
            :.|::|.:.......|.:|...::...:..|...:.|.:::.|  :.|.::|:......|::.||
Worm   131 STLSSLIRFVDSQTPVIVLDSRNLVLAVPTGDSNLDVNLEMTT--KMCGIIPIVQKETIVSSIGL 193

  Fly   293 KWNLYHAQLEFGGMVSTSNTYATEFVQVETDANLIWSMGAYEFEDKV 339
            |:.:.:..||||.::||||...|..|.:::.::||:|:   |.|:.|
Worm   194 KYEMENLALEFGKLISTSNEVTTSQVFLKSSSSLIFSI---ELENWV 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14721	NP_650110.3	TPK	100..328	CDD:153431	64/229 (28%)
CG14721	NP_650110.3	thi_PPkinase	101..330	CDD:273588	64/230 (28%)
tpk-1	NP_001023024.1	TPK	18..232	CDD:153431	66/235 (28%)
tpk-1	NP_001023024.1	PLN02714	33..233	CDD:178316	62/221 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160159209
Domainoid	1	1.000	54	1.000	Domainoid score	I7556
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6960
Inparanoid	1	1.050	97	1.000	Inparanoid score	I3612
Isobase	1	0.950	-	0	Normalized mean entropy	S2349
OMA	1	1.010	-	-		QHG54595
OrthoDB	1	1.010	-	-		D1428589at2759
OrthoFinder	1	1.000	-	-		FOG0005247
OrthoInspector	1	1.000	-	-		oto18586
orthoMCL	1	0.900	-	-		OOG6_101973
Panther	1	1.100	-	-	LDO	PTHR13622
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1532
SonicParanoid	1	1.000	-	-		X3766
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	16	15.890