DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14718 and Tex13a

DIOPT Version :9

Sequence 1:	NP_650107.1	Gene:	CG14718 / 41413	FlyBaseID:	FBgn0037939	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_080745.2	Gene:	Tex13a / 67944	MGIID:	1915194	Length:	377	Species:	Mus musculus

Alignment Length:	288	Identity:	57/288 - (19%)
Similarity:	93/288 - (32%)	Gaps:	69/288 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   122 SGESVSIDTEQ----------EAERDLQMNQCETLEREELNGDIGEM----GEMEELAEEVN-GE 171
            |..|:|.|.:|          |....|||.|.: ||..:...|:..:    .|:..|...|. ..
Mouse   103 SALSLSPDLKQLIHQQEMAQKEVALQLQMAQAK-LEEVQRERDLLRLKILQAELRALPNAVRPAV 166

  Fly   172 QRPPLLPCMGG-NTSYMVFPRTAADYMPRLALPRHRPYISIGQEQYVIQAETVFVLGMRLNVTKN 235
            ..||.:...|| .|.:.......|::|   |....||..........:..          .:|..
Mouse   167 AIPPAVVRRGGIRTQWSSTKENLAEWM---AAATGRPNERANMSDTALSG----------TITSP 218

  Fly   236 DIIL------FFGKVGVIK----------MDESTNKPKIFVYKNKITGRS-----------KGEA 273
            :.:|      |...:||:|          :|....|..:..:...:..||           ....
Mouse   219 EEVLEDPNGSFMKLLGVMKCKNYPLKRQRLDLRPKKASMCSFSQSLNLRSTVSSEPFIVQLPASF 283

  Fly   274 TITYVSPFSAQAAISCLSGAKFMGQVITVLPAYLSTRRGSVRYSYPRELNAPEHQRRQRAMKW-- 336
            |.:|.|||.|....|.|...:....|      |..:....:.:.....::..:||...:..::
Mouse   284 TYSYESPFPAIPTTSQLPTTERQPHV------YPYSMASDISHLSDMRIHRGDHQELPKDKRFSA 342

  Fly   337 --KPAIDNWVCMLCRNSNFVWRSSCNRC 362
              :|.  :|.|..|:..||..|.:|..|
Mouse   343 FRRPG--DWDCPWCKAVNFSRRENCFHC 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14718	NP_650107.1	RRM	<222..>335	CDD:223796	22/139 (16%)
		RRM_SF	223..302	CDD:302621	19/105 (18%)
		zf-RanBP	343..366	CDD:279035	8/20 (40%)
		RanBP2-type Zn finger	343..362	CDD:275375	7/18 (39%)
		zf-RanBP	397..423	CDD:295417
		RanBP2-type Zn finger	398..417	CDD:275375
Tex13a	NP_080745.2	TEX13	5..152	CDD:373629	13/49 (27%)
		ZnF_RBZ	347..369	CDD:197784	8/24 (33%)
		RanBP2-type Zn finger	349..368	CDD:275375	7/18 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842442
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930