DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14718 and taf15

DIOPT Version :9

Sequence 1:	NP_650107.1	Gene:	CG14718 / 41413	FlyBaseID:	FBgn0037939	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_001073442.1	Gene:	taf15 / 558760	ZFINID:	ZDB-GENE-061215-102	Length:	434	Species:	Danio rerio

Alignment Length:	189	Identity:	57/189 - (30%)
Similarity:	83/189 - (43%)	Gaps:	52/189 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   222 TVFVLGMRLNVTKNDIILFFGKVGVIKMDESTNKPKIFVYKNKITGRSKGEATITYVSPFSAQAA 286
            |:||.|:..:|...::..:|.::|:||:::.|.||.|.:|.:|.|||.|||||:::..|.||:||
Zfish   209 TIFVQGLGEDVNAQEVGDYFKQIGIIKVNKKTGKPMINLYSDKATGRLKGEATVSFDDPPSAKAA 273

  Fly   287 ISCLSGAKFMGQVITVLPAYLSTRRGSVRYSYPRELNAPEHQRRQRAMKWK-------------- 337
            |....|.:|.|:.|.|   ..:|||.             |..:|......:
Zfish   274 IDWFDGKEFNGRPIKV---SFATRRA-------------EFTQRGGGSGGRGGRGGFRGRGGGGG 322

  Fly   338 ----------PAID----NWVC--MLCRNSNFVWRSSCNRCQADKVVAPQNNEGSSWAG 380
                      |:.|    :|.|  ..|.|.||..|..||||...|      .||.|:.|
Zfish   323 GGGGGGFGGGPSFDVRGGDWPCPNSSCGNMNFARRYECNRCGTPK------PEGDSFGG 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14718	NP_650107.1	RRM	<222..>335	CDD:223796	39/112 (35%)
		RRM_SF	223..302	CDD:302621	32/78 (41%)
		zf-RanBP	343..366	CDD:279035	11/24 (46%)
		RanBP2-type Zn finger	343..362	CDD:275375	9/20 (45%)
		zf-RanBP	397..423	CDD:295417
		RanBP2-type Zn finger	398..417	CDD:275375
taf15	NP_001073442.1	RRM	<209..>297	CDD:223796	37/103 (36%)
		RRM_FUS_TAF15	209..291	CDD:240979	34/84 (40%)
		zf-RanBP	338..368	CDD:279035	12/35 (34%)
		RanBP2-type Zn finger	342..363	CDD:275376	9/20 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1995
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1539664at2759
OrthoFinder	1	1.000	-	-		FOG0002238
OrthoInspector	1	1.000	-	-		otm25218
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23238
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5432
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.950