DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG14718 and Fus

DIOPT Version :9

Sequence 1:NP_650107.1 Gene:CG14718 / 41413 FlyBaseID:FBgn0037939 Length:446 Species:Drosophila melanogaster
Sequence 2:NP_001012137.1 Gene:Fus / 317385 RGDID:1308864 Length:518 Species:Rattus norvegicus


Alignment Length:473 Identity:114/473 - (24%)
Similarity:158/473 - (33%) Gaps:144/473 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    10 YTNSFYAPNYSDTQQPQPQLQTQQQMFHANYIVGTTLGSGL---------------GFNFAPAPI 59
            |..|.|..:|..||......|:..|.:      |:|.|.|.               |:...|||.
  Rat    50 YGQSSYGSSYGQTQNTGYGTQSAPQGY------GSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPS 108

  Fly    60 PQASAASGLSPRGMY----SDLYRYEDGSGDASGSLLLVQEDDHFCGAEA-DQQLVASTSSSCPM 119
            ..:.:..|.|....|    |..|..:.|.|....|  ..|:...:...:. .||...::||....
  Rat   109 STSGSYGGSSQSSSYGQPQSGGYGQQSGYGGQQQS--YGQQQSSYNPPQGYGQQNQYNSSSGGGG 171

  Fly   120 ASSGESVSIDTEQEAERDLQMNQCETLEREELNGDIGEMGEMEELA----------EEVNGEQRP 174
            ...|.:...|....:.                .|..|..|..::..          ::..|..| 
  Rat   172 GGGGGNYGQDQSSMSG----------------GGGGGGYGNQDQSGGGGGGYGGGQQDRGGRGR- 219

  Fly   175 PLLPCMGGNTSYMVFPRTAADYMPR----------------------LALP-----RHRPYISIG 212
                  ||...|   .|::..|.||                      ...|     ||      .
  Rat   220 ------GGGGGY---NRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRH------D 269

  Fly   213 QEQYVIQAETVFVLGMRLNVTKNDIILFFGKVGVIKMDESTNKPKIFVYKNKITGRSKGEATITY 277
            .||......|:||.|:..|||...:..:|.::|:||.::.|.:|.|.:|.::.||:.|||||:::
  Rat   270 SEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEATVSF 334

  Fly   278 VSPFSAQAAISCLSGAKFMGQVITVLPAYLSTRR------------------------------- 311
            ..|.||:|||....|.:|.|..|.|   ..:|||                               
  Rat   335 DDPPSAKAAIDWFDGKEFSGNPIKV---SFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSG 396

  Fly   312 GSVRYSYPRELNAPEHQRRQRAMKWKPAIDNWVC--MLCRNSNFVWRSSCNRCQADKVVAPQNNE 374
            |..|..:|........|  |||..||       |  ..|.|.||.|||.||:|:|.|...|....
  Rat   397 GGGRGGFPSGGGGGGGQ--QRAGDWK-------CPNPTCENMNFSWRSECNQCKAPKPDGPGGGP 452

  Fly   375 GSSWAGSREEDGAPRRWR 392
            |.|..|...  |..||.|
  Rat   453 GGSHMGGNY--GDDRRGR 468

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG14718NP_650107.1 RRM <222..>335 CDD:223796 43/143 (30%)
RRM_SF 223..302 CDD:302621 31/78 (40%)
zf-RanBP 343..366 CDD:279035 12/24 (50%)
RanBP2-type Zn finger 343..362 CDD:275375 10/20 (50%)
zf-RanBP 397..423 CDD:295417
RanBP2-type Zn finger 398..417 CDD:275375
FusNP_001012137.1 RRM <257..>367 CDD:223796 41/118 (35%)
RRM_FUS_TAF15 276..361 CDD:240979 33/87 (38%)
zf-RanBP 415..442 CDD:279035 15/33 (45%)
RanBP2-type Zn finger 419..440 CDD:275376 12/27 (44%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1995
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D1539664at2759
OrthoFinder 1 1.000 - - FOG0002238
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR23238
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
76.880

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