DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14718 and TEX13D

DIOPT Version :9

Sequence 1:	NP_650107.1	Gene:	CG14718 / 41413	FlyBaseID:	FBgn0037939	Length:	446	Species:	Drosophila melanogaster
Sequence 2:	NP_001342463.1	Gene:	TEX13D / 100132015	HGNCID:	52278	Length:	714	Species:	Homo sapiens

Alignment Length:	318	Identity:	65/318 - (20%)
Similarity:	98/318 - (30%)	Gaps:	104/318 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 GAEADQQLVASTSSSCPMASSGESVSIDTEQEAERDLQM------NQCETLEREELNGDIGEMGE 160
            |.|..|::|.          .|::.|...|...||...|      ..|:..|..|...|......
Human   458 GPEGPQRIVL----------QGDNRSYSQEGSPERAQGMATLVFSRSCKPEEGPERPQDTPLGDS 512

  Fly   161 MEELAEEVNGEQRPPLLPCMGGNTSY--------------MVFPRTA-ADYMPRLALPRHRPYIS 210
            ...:.||  |.:.|..:...|.|.||              :||.|:. .:..|.  .|:..|
Human   513 RSHIKEE--GPEGPQRIVLQGDNRSYSQEGSPERAQGMATLVFSRSCKPEEGPE--RPQDTP--- 570

  Fly   211 IGQEQYVIQAETVFVLGMRLNVTKNDIILFFGKVG----VIKMDESTNKPKIFVYKNK-ITGRSK 270
            :|..:..|:.|                    |..|    |::.|..:       |..: ...|::
Human   571 LGDSRSHIKEE--------------------GPEGPQRIVLQGDNRS-------YSQEGSRERAQ 608

  Fly   271 GEATITYVSPFSAQAAISCLSGAKFMGQVITVLPAYLSTRRGSVRYSYPRELNAPEHQRRQRAMK 335
            |.||:.:......:.......|                |..|..|....||.......:||:|.|
Human   609 GMATLVFSRSCKPEEGPERPQG----------------TPLGDSRSHGVRESPKKWQPQRQKAKK 657

  Fly   336 WK----------------PAIDNWVCMLCRNSNFVWRSSCNRCQADKVVAPQNNEGSS 377
            .|                |...||.|..|:..||.||::|.:|:  |...|..:.|.:
Human   658 PKVNKVSGSQQQEKPASFPVPVNWKCPWCKAINFSWRTACYKCK--KACVPFESGGQT 713

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14718	NP_650107.1	RRM	<222..>335	CDD:223796	18/117 (15%)
		RRM_SF	223..302	CDD:302621	10/83 (12%)
		zf-RanBP	343..366	CDD:279035	9/22 (41%)
		RanBP2-type Zn finger	343..362	CDD:275375	8/18 (44%)
		zf-RanBP	397..423	CDD:295417
		RanBP2-type Zn finger	398..417	CDD:275375
TEX13D	NP_001342463.1	TEX13	5..148	CDD:317584
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	300..419
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	431..675		51/276 (18%)
		zf-RanBP	681..701	CDD:279035	8/19 (42%)
		RanBP2-type Zn finger	681..700	CDD:275375	8/18 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152377
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.930