DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14717 and Mest

DIOPT Version :9

Sequence 1:	NP_001262481.1	Gene:	CG14717 / 41412	FlyBaseID:	FBgn0265271	Length:	306	Species:	Drosophila melanogaster
Sequence 2:	NP_001009617.1	Gene:	Mest / 58827	RGDID:	1594589	Length:	335	Species:	Rattus norvegicus

Alignment Length:	274	Identity:	56/274 - (20%)
Similarity:	99/274 - (36%)	Gaps:	84/274 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 APPIVV-MHDLNLSLESWRQVAVNLSQVGLRQVITVDARNHGLS--PYITGHSPMHLAADVEALM 106
            :|.||| :|....|...|.::...|: :...:||.:|....|.|  |....:|....|:.||:|:
  Rat    68 SPEIVVLLHGFPTSSYDWYKIWEGLT-LRFHRVIALDFLGFGFSDKPRPHQYSIFEQASIVESLL 131

  Fly   107 SHQRL--NKIVALGHGMG----------------GR-AMMTLALT---------QPQLVERVILV 143
            .|..|  .:|..|.|..|                || .:.:|.|:         :|.|:::::..
  Rat   132 RHLGLQNRRINLLSHDYGDIVAQELLYRYKQNRSGRLTIKSLCLSNGGIFPETHRPLLLQKLLKD 196

  Fly   144 DITPAPVPS---NFYL------------TRQVFEMMLQVAPSIPSNLSLSEGRTFILPLFQDVVH 193
            ....:|:.:   ||::            ||.....:..:...|.:|    :|...|..|.| .::
  Rat   197 GGVLSPILTRLMNFFVFSRGLTPVFGPYTRPTESELWDMWAGIRNN----DGNLVIDSLLQ-YIN 256

  Fly   194 DASELRR--------------IIY----------NLRKMQDNTFGWAVNPQAVLSSWGEMMINY- 233
            ...:.||              .||          ...::...|.     |::.:|...:.:.:|
  Rat   257 QRKKFRRRWVGALASVTIPIHFIYGPLDPINPYPEFLELYRKTL-----PRSTVSILDDHISHYP 316

  Fly   234 --EATLGGLRPYMG 245
              |..:|.|..|||
  Rat   317 QLEDPMGFLNAYMG 330

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14717	NP_001262481.1	MhpC	28..299	CDD:223669	56/274 (20%)
		Abhydrolase_5	47..>165	CDD:289465	35/163 (21%)
		Abhydrolase	<249..301	CDD:304388
Mest	NP_001009617.1	MhpC	47..321	CDD:223669	51/263 (19%)
Mest	NP_001009617.1	RVIALD	98..103		2/4 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1268438at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010