Protein Alignment CG14717 and NDRG3

DIOPT Version :10

• Sequence 1: NP_650106.1
• Gene: CG14717 / 41412
• FlyBaseID: FBgn0265271
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: XP_006723900.1
• Gene: NDRG3 / 57446
• HGNCID: 14462
• Length: 388
• Species: Homo sapiens
• Alignment Length: 326
• Identity: 77/326 - (23%)
• Similarity: 126/326 - (38%)
• Gaps: 81/326 - (24%)

  Fly    20 RNFQSF------VQGTR-LEYVSYTS-PRNQMQAPPIVVMHDLNLSLESWRQVAVNLSQVGLRQV 76
            ||||.|      ::.|. :.:|:... |:.  ..|.|:..||:.|:.:|......|...:   |.
Human    23 RNFQDFDCQEHDIETTHGVVHVTIRGLPKG--NRPVILTYHDIGLNHKSCFNAFFNFEDM---QE 82

  Fly    77 IT-------VDA--RNHGLSPYITGHS-PM--HLAADVEALMSHQRLNKIVALGHGMGGRAMMTL 129
            ||       |||  :..|...:.||:. |.  .||..:..:::|..|..|:.:|.|.|...:...
Human    83 ITQHFAVCHVDAPGQQEGAPSFPTGYQYPTMDELAEMLPPVLTHLSLKSIIGIGVGAGAYILSRF 147

  Fly   130 ALTQPQLVERVILVDITPAP------VPSNFY-LTRQVFEMMLQ---VAPSIPSNLSLSEGRTFI 184
            ||..|:|||.::|:::.|..      ..|... ||..|.:::|.   ....:.:||.|.:  |:.
Human   148 ALNHPELVEGLVLINVDPCAKGWIDWAASKLSGLTTNVVDIILAHHFGQEELQANLDLIQ--TYR 210

  Fly   185 LPLFQDVVHDASELRRIIYNLRKMQDNTFGWAVNPQAVLSSW-GEMMINYEATLGGLRPYMGE-- 246
            :.:.||:..|                       |.|..|:|: |...:..|      ||.:|:
Human   211 MHIAQDINQD-----------------------NLQLFLNSYNGRRDLEIE------RPILGQND 246

  Fly   247 ---------VLLIAGSQSEFVTTTSIAVMQRYFP--NTVVQILDAGHCVYEDQPEQFVELVVEFT 300
                     .||:.|..|..|... :....|..|  .|::::.|.|......||.:..|....|.
Human   247 NKSKTLKCSTLLVVGDNSPAVEAV-VECNSRLNPINTTLLKMADCGGLPQVVQPGKLTEAFKYFL 310

  Fly   301 Q 301
            |
Human   311 Q 311

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14717	NP_650106.1	MenH	26..299	CDD:440361	70/310 (23%)
NDRG3	XP_006723900.1	Ndr	32..317	CDD:397285	72/317 (23%)