Protein Alignment CG14717 and ABHD5

DIOPT Version :9

• Sequence 1: NP_001262481.1
• Gene: CG14717 / 41412
• FlyBaseID: FBgn0265271
• Length: 306
• Species: Drosophila melanogaster
• Sequence 2: NP_001342115.1
• Gene: ABHD5 / 51099
• HGNCID: 21396
• Length: 349
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 72/304 - (23%)
• Similarity: 112/304 - (36%)
• Gaps: 81/304 - (26%)

  Fly    47 PIVVMHDLNLSLESWRQVAVNLSQVGL-RQVITVDARNHGLSPYITGHSPMHLAADVEALMSH-- 108
            |:|::|.....|..|   |:|...:.. |.|...|....|.|      |.....:|.|.:.:.
Human    77 PLVLLHGFGGGLGLW---ALNFGDLCTNRPVYAFDLLGFGRS------SRPRFDSDAEEVENQFV 132

  Fly   109 ---------QRLNKIVALGHGMGGRAMMTLALTQPQLVERVILVDITPAPVPSNFYLTRQ----- 159
                     ..|:|::.|||.:||......:|..|..|..:|||:  |...|....|..|
Human   133 ESIEEWRCALGLDKMILLGHNLGGFLAAAYSLKYPSRVNHLILVE--PWGFPERPDLADQDRPIP 195

  Fly   160 -----------VFEMMLQVAPSIPSNLSLSEGRTFILP--------LFQDVVHDASELRRIIY-- 203
                       .|..:..:..:.|..|||.:.   :.|        :|:|     ..:...||
Human   196 VWIRALGAALTPFNPLAGLRIAGPFGLSLVQR---LRPDFKRKYSSMFED-----DTVTEYIYHC 252

  Fly   204 NLRKMQDNT--------FGWAVNPQAVLSSWGEMMINYEATLGGLRPYMGEVLLIAGSQS--EFV 258
            |::.....|        :|||..|..             ..:|.:.|.: .|.:|.|::|  :..
Human   253 NVQTPSGETAFKNMTIPYGWAKRPML-------------QRIGKMHPDI-PVSVIFGARSCIDGN 303

  Fly   259 TTTSIAVMQRYFPNTVVQILDAGHCVYEDQPEQFVELVVEFTQT 302
            :.|||..::.:.....:.||.|||.||.||||:|.:.|.|...|
Human   304 SGTSIQSLRPHSYVKTIAILGAGHYVYADQPEEFNQKVKEICDT 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14717	NP_001262481.1	MhpC	28..299	CDD:223669	70/299 (23%)
		Abhydrolase_5	47..>165	CDD:289465	33/145 (23%)
		Abhydrolase	<249..301	CDD:304388	20/53 (38%)
ABHD5	NP_001342115.1	Abhydrolase_1	1..345	CDD:331148	71/300 (24%)
		HXXXXD motif	327..332		3/4 (75%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR42886
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010