DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer3 and MSC

DIOPT Version :9

Sequence 1:	NP_524322.1	Gene:	Fer3 / 41411	FlyBaseID:	FBgn0037937	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_005089.2	Gene:	MSC / 9242	HGNCID:	7321	Length:	206	Species:	Homo sapiens

Alignment Length:	157	Identity:	44/157 - (28%)
Similarity:	64/157 - (40%)	Gaps:	61/157 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly    62 PSTNGRAN----------------GSSSSSKKTRRRVA--------------------------S 84
            ||.|..|.                ||:...|:.|.|||                          .
Human    41 PSDNSSAEEEDPDGEEERCALGTAGSAEGCKRKRPRVAGGGGAGGSAGGGGKKPLPAKGSAAECK 105

  Fly    85 MAQRRAANIRERRRMFNLNEAFDKLRRKVPTFAYEKRLSRIETLRLAITYIGFMAELLSGTPSNS 149
            .:||.|||.|||.||..|::||.:|:..:|....:.:||:::|||||.:||..:.:||
Human   106 QSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIAHLRQLL------- 163

  Fly   150 HKSRSDVYGSMNGHHQAPPPAIHPHHL 176
               :.|.|  .||:       :||.:|
Human   164 ---QEDRY--ENGY-------VHPVNL 178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer3	NP_524322.1	HLH	87..135	CDD:278439	22/47 (47%)
MSC	NP_005089.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..115		16/73 (22%)
		Nuclear localization signal. /evidence=ECO:0000255	71..76		2/4 (50%)
		bHLH_TS_musculin	105..170	CDD:381546	28/76 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810