DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer3 and BHLHA9

DIOPT Version :9

Sequence 1:	NP_524322.1	Gene:	Fer3 / 41411	FlyBaseID:	FBgn0037937	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_001157877.1	Gene:	BHLHA9 / 727857	HGNCID:	35126	Length:	235	Species:	Homo sapiens

Alignment Length:	162	Identity:	52/162 - (32%)
Similarity:	73/162 - (45%)	Gaps:	39/162 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 GFPCTDLSLWQRSQVTPLVPQRPSTNG--RANGSSSS--------SKKTRRRVASMAQRRAANIR 94
            |.||               |:....:|  .|||:|.|        .::..|.|.|.|:|.|||:|
Human    24 GGPC---------------PEPGGDSGVLGANGASCSRGEAEEPAGRRRARPVRSKARRMAANVR 73

  Fly    95 ERRRMFNLNEAFDKLRRKVPTFAYEKRLSRIETLRLAITYIGFMAELLSGTPS----------NS 149
            ||:|:.:.||||:.|||.:......||||:|.|||.||..|..::.:|..:|:          :.
Human    74 ERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRASPAPRGPCGHLECHG 138

  Fly   150 HKSRSDVYGSMNGHHQAPPPAIHPHHLHPAAA 181
            ..:|.|. |....   :|||...|....|.||
Human   139 PAARGDT-GDTGA---SPPPPAGPSLARPDAA 166

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer3	NP_524322.1	HLH	87..135	CDD:278439	25/47 (53%)
BHLHA9	NP_001157877.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..69		15/59 (25%)
		HLH	66..117	CDD:278439	26/50 (52%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	132..235		10/39 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	60	1.000	Inparanoid score	I5396
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.960