DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fer3 and Atoh8

DIOPT Version :9

Sequence 1:	NP_524322.1	Gene:	Fer3 / 41411	FlyBaseID:	FBgn0037937	Length:	195	Species:	Drosophila melanogaster
Sequence 2:	NP_722473.1	Gene:	Atoh8 / 71093	MGIID:	1918343	Length:	322	Species:	Mus musculus

Alignment Length:	158	Identity:	46/158 - (29%)
Similarity:	67/158 - (42%)	Gaps:	38/158 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 PFQPLWGQEAP-PPPIVPYQELIAGFPCTDLSLWQRSQVTPLVPQRPST-----------NGRAN 69
            |.:|.  |.|| .||..|                |.|.|.|..|.||..           |...:
Mouse   160 PARPT--QSAPLAPPAAP----------------QESPVRPAPPTRPGESSYSSISHVIYNNHPD 206

  Fly    70 GSSSSSKK--------TRRRVASMAQRRAANIRERRRMFNLNEAFDKLRRKVPTFAYEKRLSRIE 126
            .|:|..|:        |..:.....:|..||.|||.|:..::.||:.||::||.::|.::||::.
Mouse   207 SSASPRKRPGEATAASTEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLA 271

  Fly   127 TLRLAITYIGFMAELLSGTPSNSHKSRS 154
            .||:|..||..:|.|.....|..|.:.|
Mouse   272 ILRIACNYILSLARLADLDYSADHSNLS 299

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fer3	NP_524322.1	HLH	87..135	CDD:278439	19/47 (40%)
Atoh8	NP_722473.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	77..96
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	101..144
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	159..221		19/78 (24%)
		Basic motif, degenerate. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00981	231..244		6/12 (50%)
		HLH	232..283	CDD:278439	21/50 (42%)
		Helix-loop-helix motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00981	245..283		14/37 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910